Predictors of hip fracture in 15 European countries: a longitudinal study of 48,533 geriatric adults using SHARE dataset.

Autor: Hussain MA; Department of Finance and Economics, College of Business Administration, University of Sharjah, Sharjah, 27272, UAE.; Department of Social Sciences and Business, Roskilde University, 4000, Roskilde, Denmark., Qaisar R; Basic Medical Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates.; Cardiovascular Research Group, Research Institute for Medical and Health Sciences, University of Sharjah, 27272, Sharjah, United Arab Emirates., Karim A; Basic Medical Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates., Ahmad F; Basic Medical Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates.; Cardiovascular Research Group, Research Institute for Medical and Health Sciences, University of Sharjah, 27272, Sharjah, United Arab Emirates., Franzese F; SHARE Berlin Institute, Chausseestraße 111, 10115, Berlin, Germany., Awad A; Department of Finance and Economics, College of Business Administration, University of Sharjah, Sharjah, 27272, UAE., Al-Masri AA; Department of Physiology, College of Medicine, King Saud University, 11451, Riyadh, Saudi Arabia., Alsaeed M; Department of Biomechanics & Motor Behavior, College of Sport Sciences and Physical Activity, King Saud University, 11451, Riyadh, Saudi Arabia., Alkahtani SA; Exercise Physiology Department, College of Sport Sciences and Physical Activity, King Saud University, PO Box: 1949, 11451, Riyadh, Saudi Arabia. shalkahtani@ksu.edu.sa.
Jazyk: angličtina
Zdroj: Archives of osteoporosis [Arch Osteoporos] 2024 Jul 18; Vol. 19 (1), pp. 60. Date of Electronic Publication: 2024 Jul 18.
DOI: 10.1007/s11657-024-01420-4
Abstrakt: We investigated the risk factors for hip fracture in 48,533 European older adults for 8 years from 2013 onward. We identified female gender, age above 80, low handgrip strength, and depression as significant risk factors for hip fracture. Our findings may help identify high-risk populations for hip fractures in pre-clinical settings.
Objectives: Hip fracture is a major cause of functional disability, mortality, and health costs. However, the identification and characterization of its causative factors remain poor.
Methods: We investigated demography, handgrip strength (HGS), depression, and multiple age-associated comorbidities for predicting future hip fracture in individuals aged 50 or above from 15 European countries (n = 48,533). All participants were evaluated from 2013 to 2020 using four successive waves of the Survey of Health, Aging, and Retirement in Europe (SHARE).
Results: Altogether, 1130 participants developed hip fractures during the study period. We identified female gender, an advancing age from quinquagenarians onward, and a poor socioeconomic status as critical risk factors for future hip fracture. Having mobility difficulty, a low HGS (< 27 kg in men, < 16 kg in women) and higher scores on Euro-D depression scales were also significant risk factors for hip fracture. Summated scales of hypertension, diabetes mellitus, cancer, Alzheimer's disease, and stroke did not appear as risk factors.
Conclusion: Collectively, we report advancing age, female gender, low HGS, and depression as independent risk factors for hip fracture. Our findings are useful in identifying high-risk populations for hip fractures in pre-clinical settings before rigorous evaluation and treatment in clinics.
(© 2024. International Osteoporosis Foundation and Bone Health and Osteoporosis Foundation.)
Databáze: MEDLINE
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