Primary mucosal malignant melanoma (PMMM) of nasal cavity: A report of two cases.

Autor: Chaturvedi A; Department of Pathology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India., Mallya V; Department of Pathology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India., Mandal S; Department of Pathology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India., Khurana N; Department of Pathology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India., Meher R; Department of Otolaryngology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India., Singh K; Department of Radiotherapy, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Jazyk: angličtina
Zdroj: Journal of cancer research and therapeutics [J Cancer Res Ther] 2024 Apr 01; Vol. 20 (3), pp. 1053-1056. Date of Electronic Publication: 2024 Jun 27.
DOI: 10.4103/jcrt.jcrt_2029_22
Abstrakt: Abstract: Primary mucosal malignant melanoma of the nasal cavity is a rare tumor with aggressive behavior and a dismal prognosis. An extremely rare tumor that accounts for 0.7% to 1% of all melanomas in Caucasian populations and between 4% and 8% of malignant tumors of the nasal cavity and paranasal sinuses. Taking into account the rarity, it is important to note that malignant melanoma should be considered when making a differential diagnosis of tumors of the nose and paranasal sinuses. Two cases of primary malignant melanoma of the nasal cavity both arising in females, one in a 60-year-old and the other in a 64-year-old, both of whom presented with nasal obstruction and brief symptomatic epistaxis are being presented here. The diagnosis being confirmed by a histopathological examination along with an immunohistochemical analysis by using S100 and HMB45.
(Copyright © 2024 Copyright: © 2024 Journal of Cancer Research and Therapeutics.)
Databáze: MEDLINE