The impact of the COVID-19 pandemic on TB notifications in Ukraine in 2020.

Autor:	Shapiro AN; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Dolynska M; NGO Infection Control Ukraine, Kyiv, Ukraine., Chiang SS; Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI, USA.; Center for International Health Research, Rhode Island Hospital, Providence, RI, USA., Rybak N; Department of Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USA., Petrenko V; Bogomolets National Medical University, Kyiv, Ukraine., Horsburgh CR Jr; Departments of Global Health, Epidemiology, Biostatistics and Medicine, Boston University, Boston, MA, USA., Kobe J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Terleieva I; Public Health Center of the Ministry of Health, Kyiv City, Ukraine., Sakalska O; Public Health Center of the Ministry of Health, Kyiv City, Ukraine., Jenkins HE; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Jazyk:	angličtina
Zdroj:	IJTLD open [IJTLD Open] 2024 Jun 01; Vol. 1 (6), pp. 258-265. Date of Electronic Publication: 2024 Jun 01 (Print Publication: 2024).
DOI:	10.5588/ijtldopen.24.0194
Abstrakt:	Background: We assessed the impact of the COVID-19 pandemic on TB notifications in Ukraine, stratified by multiple subgroups. Design/methods: We analyzed data from Ukraine's National TB Program from January 2015 to December 2020 using interrupted time series models. We compared observed cases to counterfactual estimated cases had the pandemic not occurred and estimated trends through December 2020 nationally and by various demographics. We compared the proportions of individuals who underwent drug susceptibility testing (DST) in February 2020 and April 2020 to assess the pandemic impact on drug resistance testing. Results: In April 2020, there were 39% (95% CI 36-42) fewer TB notifications than the estimated counterfactual (3,060 estimated; 95% CI 2,918-3,202; 1,872 observed). We observed a greater decrease in notifications among refugees/migrants compared with non-refugees/migrants (64%, 95% CI 60-67 vs. 39%, 95% CI 36-42), and individuals aged <15 years compared with those aged ≥15 years (60%, 95% CI 57-64 vs. 38%, 95% CI 36-41). We also observed a decrease in the proportion of individuals receiving DST for several drugs. Conclusions: These findings underscore the challenges to TB prevention and care during disruption and may be generalizable to the current wartime situation, especially considering the substantial increase in refugees within and leaving Ukraine. (© 2024 The Authors.)
Databáze:	MEDLINE
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