Cancers attributable to tobacco smoking in Italy in 2020.

Autor: Collatuzzo G; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Malvezzi M; Department of Medicine and Surgery, University of Parma, Parma, Italy., Mangiaterra S; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Di Maso M; Department of Clinical Sciences and Community Health, University of Milan, Milan., Turati F; Department of Clinical Sciences and Community Health, University of Milan, Milan., Parazzini F; Department of Clinical Sciences and Community Health, University of Milan, Milan., Pelucchi C; Department of Clinical Sciences and Community Health, University of Milan, Milan., Alicandro G; Cystic Fibrosis Centre, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Negri E; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., La Vecchia C; Department of Clinical Sciences and Community Health, University of Milan, Milan., Boffetta P; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; Stony Brook Cancer Center, Stony Brook University, Stony Brook, NY, USA. Electronic address: paolo.boffetta@stonybrookmedicine.edu.
Jazyk: angličtina
Zdroj: Cancer epidemiology [Cancer Epidemiol] 2024 Jul 16; Vol. 92, pp. 102623. Date of Electronic Publication: 2024 Jul 16.
DOI: 10.1016/j.canep.2024.102623
Abstrakt: Background: Tobacco smoking is still frequent in Italy and a major cause of cancer globally. We estimated the burden of smoking-related cancer in Italy.
Methods: To calculate the population attributable fraction (PAF), we adopted a counterfactual scenario for which all individuals never smoked. The PAF of current and former smoking and second-hand smoke (SHS) was estimated for cancers associated with these habits according to the International Agency for Research on Cancer. Relative risk estimates and prevalence of exposure were derived from large-scale studies and national surveys, respectively. A 20-year latency period between exposure and cancer was considered. Cancer incidence data for 2020 and mortality data for 2017 were obtained from the Italian Association of Cancer Registries.
Results: Tobacco smoking caused, in men and women respectively, 90.0 % and 58.3 % of lung; 67.8 % and 53.5 % of pharyngeal; 47.0 % and 32.2 % of bladder; 45.9 % and 31.7 % of oral; 36.6 % and 23.6 % of esophageal; 23.0 % and 14.0 % of pancreatic cancer and lower percentages of cancers at other sites. Tobacco smoking accounted for 23.9 % and 7.7 % of new cancer cases in 2020, and 32.1 % and 11.3 % of cancer deaths in 2017 in men and women, respectively, corresponding to 17.3 % of cases and 24.5 % of cancer deaths overall. The PAF of lung cancer due to SHS in never smoking women married with smokers was 13.0 %.
Conclusions: Tobacco smoking is a primary cause of cancer in Italy in both sexes. Tobacco control policies are warranted.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this article.
(Copyright © 2024. Published by Elsevier Ltd.)
Databáze: MEDLINE
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