Recovery rate after acute acoustic trauma: a case series and meta-analysis.

Autor: Welber S; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.; School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Oron Y; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.; School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Handzel O; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.; School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Abu-Eta R; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.; School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Muhanna N; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.; School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Shilo S; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.; School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Ungar OJ; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel. ungaromer@gmail.com.; School of Medicine, Tel-Aviv University, Tel Aviv, Israel. ungaromer@gmail.com.
Jazyk: angličtina
Zdroj: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2024 Dec; Vol. 281 (12), pp. 6303-6316. Date of Electronic Publication: 2024 Jul 17.
DOI: 10.1007/s00405-024-08847-y
Abstrakt: Objective: Steroids given systemically, locally, or both are the mainstay of treatment for acute acoustic trauma (AAT). The overall recovery rate (full, partial, and none) is undetermined.
Study Design: Original case series and systematic literature review.
Setting: Case series of a tertiary referral center and a systematic literature review.
Methods: Cases of AAT between 2012 and 2022 were retrospectively analyzed for demographics, acoustic trauma characteristics, treatment modality and delay and prognosis. This case series was added to the series identified by a systematic literature review. This review included "Medline" via "PubMed", "EMBASE", and "Google scholar". All series were pooled for meta-analysis defining prognosis following steroidal treatment for AAT patients.
Results: The pooled analyses included 662 ears, out of which 250 underwent complete recovery of hearing (overall proportion = 0.2809, 95%confidence interval [CI] = 0.1611-0.4178). Any recovery was recorded for 477 ears (overall proportion = 0.7185, 95% CI = 0.5671-0.8493) and no recovery was documented for 185 ears (overall proportion = 0.2815, 95% CI = 0.1507-0.4329).
Conclusion: The rate of overall recovery for AAT is around 70%, and around 30% for full recovery when steroids are initiated within the first 2 weeks following the insult.
Competing Interests: Declarations Conflict of interest The authors have no financial conflicts of interest relevant to this article to disclose. Ethical consideration This retrospective medical record review was approved by the institutional review board of the Tel Aviv Sourasky Medical Center (0312-19-TLV) which waived informed consent.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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