Mammographic density in relationships with relevant contributing factors: a multicentric study from Riyadh, Saudi Arabia.

Autor:	AlSaleh N; Department of Surgery, College of Medicine, King Saud University Medical City (KSUMC), Riyadh, Saudi Arabia., AlRammah T; Department of Surgery, Diriayah Hospital, Riyadh Third Health Cluster Ministry of Health, Riyadh, Saudi Arabia., Alatabani A; Department of Surgery, Dr. Sulaiman Al Habib Hospital, Riyadh, Saudi Arabia., Alsalem A; Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia., Alsheikh T; Faculty of Medicine, Alfaisal University, Riyadh, Saudi Arabia., AlRabah R; Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia., Al-Qattan N; Department of Surgery, College of Medicine, King Saud University Medical City (KSUMC), Riyadh, Saudi Arabia., Alhomod A; Ministry of Health, Riyadh, Saudi Arabia., Alkhaldi T; Department of Surgery, College of Medicine, King Saud University Medical City (KSUMC), Riyadh, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Gland surgery [Gland Surg] 2024 Jun 30; Vol. 13 (6), pp. 844-851. Date of Electronic Publication: 2024 Jun 27.
DOI:	10.21037/gs-23-374
Abstrakt:	Background: Mammographic breast density (MBD), a well-established factor linked to breast cancer, is the focus of this preliminary report among women across multiple centers in Riyadh. The study aims to identify risk factors associated with high breast density. Methods: MBD was assessed at three hospitals in Riyadh, Saudi Arabia, using the American College of Radiology (ACR) categories: A (almost entirely fatty), B (scattered areas of fibroglandular density), C (heterogeneously dense), and D (extremely dense). Breast density distributions were analyzed in relation to age, body mass index (BMI), family history, parity, and hormonal therapy usage. Results: The study included 1,530 women, revealing an inverse association between dense breast proportion and age/BMI. Notably, 43.3% [95% confidence interval (CI): 43.2% to 43.5%] of women aged 40-79 years exhibited heterogeneously or highly dense breasts, with this proportion inversely correlated with age and BMI. Conclusions: Healthcare providers should consider breast density for appropriate screening and, if necessary, recommend supplemental methods. Policymakers and healthcare providers, when discussing breast density notification legislation, should be mindful of its high prevalence, ensuring women notified have opportunities to evaluate breast cancer risk and pursue supplemental screening options if deemed appropriate. Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://gs.amegroups.com/article/view/10.21037/gs-23-374/coif). The authors have no conflicts of interest to declare. (2024 Gland Surgery. All rights reserved.)
Databáze:	MEDLINE
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