Idiopathic sudden sensorineural hearing loss after COVID-19 vaccination: a systematic review and meta-analysis.

Autor: Alper L; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Affiliated to the School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Oron Y; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Affiliated to the School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Handzel O; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Affiliated to the School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Abu-Eta R; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Affiliated to the School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Muhanna N; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Affiliated to the School of Medicine, Tel-Aviv University, Tel Aviv, Israel., Ungar OJ; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. ungaromer@gmail.com.; Affiliated to the School of Medicine, Tel-Aviv University, Tel Aviv, Israel. ungaromer@gmail.com.
Jazyk: angličtina
Zdroj: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2024 Dec; Vol. 281 (12), pp. 6275-6281. Date of Electronic Publication: 2024 Jul 16.
DOI: 10.1007/s00405-024-08839-y
Abstrakt: Objective: To provide pooled analyses on the association between COVID-19 vaccine and the incidence of idiopathic sudden sensorineural hearing loss (ISSNHL).
Data Sources: "Medline" via "PubMed", "EMBASE", and "Google scholar".
Review Methods: Data sources were inspected from January 2020 to January 2024 using search terms relevant to vaccines for COVID-19. Included were papers with reported numbers of vaccinated populations and incidence if ISSNHL in those populations. Quality assessment was performed with the Newcastle-Ottawa Quality Assessment Scale Criteria.
Results: Three publications encompassing more than 191.8 million patients and at least 283 million vaccine doses were included in the quantitative data synthesis. The pooled reported incidence (95%confidence interval) of ISSNHL among COVID-19 vaccine recipients was 1.2588 per 100,000 (0.1385-3.4836). This incidence is significantly lower than the incidence of 5-27 and 60 per 100,000/year reported in the United States and in the European Union, respectively (P < 0.0001).
Conclusion: There is no evidence to indicate that the COVID-19 vaccine is associated with the incidence of ISSNHL.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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