Genetic admixture drives climate adaptation in the bank vole.

Autor: Horníková M; Laboratory of Molecular Ecology, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Liběchov, Czech Republic., Lanier HC; Department of Biology, Program in Ecology & Evolutionary Biology, University of Oklahoma, Norman, OK, USA.; Sam Noble Museum, University of Oklahoma, Norman, OK, USA., Marková S; Laboratory of Molecular Ecology, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Liběchov, Czech Republic., Escalante MA; Laboratory of Molecular Ecology, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Liběchov, Czech Republic., Searle JB; Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY, USA., Kotlík P; Laboratory of Molecular Ecology, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Liběchov, Czech Republic. kotlik@iapg.cas.cz.
Jazyk: angličtina
Zdroj: Communications biology [Commun Biol] 2024 Jul 15; Vol. 7 (1), pp. 863. Date of Electronic Publication: 2024 Jul 15.
DOI: 10.1038/s42003-024-06549-z
Abstrakt: Genetic admixture introduces new variants at relatively high frequencies, potentially aiding rapid responses to environmental changes. Here, we evaluate its role in adaptive variation related to climatic conditions in bank voles (Clethrionomys glareolus) in Britain, using whole-genome data. Our results reveal loci showing excess ancestry from one of the two postglacial colonist populations inconsistent with overall admixture patterns. Notably, loci associated with climate adaptation exhibit disproportionate amounts of excess ancestry, highlighting the impact of admixture between colonist populations on local adaptation. The results suggest strong and localized selection on climate-adaptive loci, as indicated by steep clines and/or shifted cline centres, during population replacement. A subset, including a haemoglobin gene, is associated with oxidative stress responses, underscoring a role of oxidative stress in local adaptation. Our study highlights the important contribution of admixture during secondary contact between populations from distinct climatic refugia enriching adaptive diversity. Understanding these dynamics is crucial for predicting future adaptive capacity to anthropogenic climate change.
(© 2024. The Author(s).)
Databáze: MEDLINE
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