Cardiomegaly: Navigating the uncharted territories of heart failure - A multimodal radiological journey through advanced imaging, pathophysiological landscapes, and innovative therapeutic frontiers.

Autor: Iqbal MK; Liaoning Provincial Key Laboratory of Cerebral Diseases, Department of Physiology, Dalian Medical University Liaoning Provence China; Department of Biochemistry, Government College University, Faisalabad, Pakistan., Ambreen A; Department of Biochemistry, Government College University, Faisalabad, Pakistan., Mujahid M; Department of Biochemistry, Government College University, Faisalabad, Pakistan., Zarlashat Y; Department of Biochemistry, Government College University, Faisalabad, Pakistan., Abid M; Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China., Yasin A; Department of Pathology and Forensic Medicine, Dalian Medical University Liaoning Provence, China., Ullah MN; University of Health Sciences, Lahore, Pakistan., Shahzad R; Research Center for Genetic Engineering, National Research and Innovation Agency (BRIN), KST-Cibinong, JI Raya Bogor KM46, Cibinong 16911, Indonesia., Harlina PW; Department of Food Industrial Technology, Faculty of Agro-Industrial Technology, Universitas Padjadjaran, 45363 Bandung, Indonesia., Khan SU; Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City and Southwest University, College of Agronomy and Biotechnology, Southwest University, Chongqing, 400715, China; Women Medical and Dental College, Khyber Medical University, Peshawar, KPK, 22020, Pakistan. Electronic address: shahid.zkd35@yahoo.com., Alissa M; Department of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia., Algopishi UB; Department of Biology, College of Science, King Khalid University, 61413 Abha, Saudi Arabia., Almubarak HA; Division of Radiology, Department of Medicine, College of Medicine and Surgery, King Khalid University, Abha, Saudi Arabia.
Jazyk: angličtina
Zdroj: Current problems in cardiology [Curr Probl Cardiol] 2024 Sep; Vol. 49 (9), pp. 102748. Date of Electronic Publication: 2024 Jul 14.
DOI: 10.1016/j.cpcardiol.2024.102748
Abstrakt: Cardiomegaly is among the disorders categorized by a structural enlargement of the heart by any of the situations including pregnancy, resulting in damage to heart muscles and causing trouble in normal heart functioning. Cardiomegaly can be defined in terms of dilatation with an enlarged heart and decreased left or biventricular contraction. The genetic origin of cardiomegaly is becoming more evident due to extensive genomic research opening up new avenues to ensure the use of precision medicine. Cardiomegaly is usually assessed by using an array of radiological modalities, including computed tomography (CT) scans, chest X-rays, and MRIs. These imaging techniques have provided an important opportunity for the physiology and anatomy of the heart. This review aims to highlight the complexity of cardiomegaly, highlighting the contribution of both ecological and genetic variables to its progression. Moreover, we further highlight the worth of precise clinical diagnosis, which comprises blood biomarkers and electrocardiograms (EKG ECG), demonstrating the significance of distinguishing between numerous basic causes. Finally, the analysis highlights the extensive variation of treatment lines, such as lifestyle modifications, prescription drugs, surgery, and implantable devices, although highlighting the critical need for individualized and personalized care.
Competing Interests: Declaration of competing interest The authors declared that they have no competing interests among them.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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