Comparative effects of 8-week combined resistance exercise training and alternate-day calorie restriction on soluble epidermal growth factor receptor (sEGFR) and adipsin in obese men.

Autor: Hikmat Y; Department of Exercise Physiology, Faculty of Sport Sciences, University of Mazandaran, Babolsar, Iran., Safarzade A; Department of Exercise Physiology, Faculty of Sport Sciences, University of Mazandaran, Babolsar, Iran.; Athletic Performance and Health Research Center, University of Mazandaran, Babolsar, Iran., Alizadeh H; PhD in Exercise Physiology, University of Mazandaran, Babolsar, Iran.
Jazyk: angličtina
Zdroj: Growth factors (Chur, Switzerland) [Growth Factors] 2024 Aug; Vol. 42 (3), pp. 111-119. Date of Electronic Publication: 2024 Jul 15.
DOI: 10.1080/08977194.2024.2378889
Abstrakt: This study investigated the combined effects of resistance exercise training (RET) and alternate-day calorie restriction (ADCR) on body composition, insulin resistance (IR), insulin resistance-related biomarkers (adipokine adipsin and hepatokine soluble EFGR), and weight loss in obese men. The findings revealed that RET + ADCR induced the greatest reductions in body weight, body fat percentage, and waist-to-hip ratio (WHR) compared to RET and ADCR alone ( p  < 0.05). Additionally, RET + ADCR resulted in the most significant improvements in IR, as measured by HOMA-IR, and in circulating levels of adipsin and soluble EFGR ( p  < 0.05). These findings suggest that combining RET and ADCR may be a more effective strategy for improving metabolic health, including body composition, IR, and metabolic tissues' functions, in obese men than either intervention alone.
Databáze: MEDLINE