| Autor: |
Nedumaran N; Department of Periodontology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India., Rajasekar A; Department of Periodontology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India. |
| Jazyk: |
angličtina |
| Zdroj: |
Photobiomodulation, photomedicine, and laser surgery [Photobiomodul Photomed Laser Surg] 2024 Aug; Vol. 42 (8), pp. 561-567. Date of Electronic Publication: 2024 Jul 15. |
| DOI: |
10.1089/pho.2024.0037 |
| Abstrakt: |
Aim: The study aims to assess the efficacy of rose bengal (RB)-mediated antimicrobial photodynamic therapy (a-PDT) as an adjunct to scaling and root planing in the management of chronic periodontitis patients in terms of clinical parameters like gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), and microbiological parameters like total microbial count, total red complex organism count, Porphyromonas gingivalis count, Treponema denticola count, and Tannerella forsythia count. Materials and Methods: In this randomized controlled clinical trial, a total of 30 patients were recruited who met the inclusion criteria. The participants were randomly allocated into group A with scaling and root planning (SRP) alone and group B with SRP + a-PDT. The clinical and microbiological parameters were measured at baseline and at 3-month follow-up. Intergroup and intragroup comparisons were performed using independent t test and paired t test, respectively. Value of p < 0.05 was considered as statistically significant. Results: At 3-month follow-up, group B treated with SRP + a-PDT showed statistically significant reduction in GI (0.58 ± 0.20) and PPD (1.81 ± 0.32 mm), gain in CAL (0.73 ± 0.04 mm), and reduction in total microbial count [2.80 ± 0.08 × 10 4 colony forming unit (CFU)], total red complex count (0.29 ± 0.14 × 10 2 CFU), P. gingivalis count (0.43 ± 0.13 × 10 2 CFU), T. denticola count (0.61 ± 0.04 × 10 2 CFU), and T. forsythia count (0.59 ± 0.04 × 10 2 CFU) as compared with group A ( p < 0.05). Conclusion: RB-mediated a-PDT as an adjunct to SRP was significantly more effective in improving GI, PPD, and CAL and in reducing microbial count as compared with SRP alone in the management of chronic periodontitis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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