Comparative study of the severity of Covid-19 infection between female and male patients.
| Autor: | Imzil A; Pneumology Department, Faculty of Medicine and Pharmacy of Agadir, Souss-Massa University Hospital, Ibn Zohr University, Agadir, Morocco., Mansoury O; Clinical Research Department, Mohammed VI University Hospital, Marrakesh, Morocco.; Community Medicine and Public Health Department, Bioscience and Health Research Laboratory, School of Medicine, Cadi Ayyad University, Marrakesh, Morocco., Oulahbib A; Pneumology Department, Faculty of Medicine and Pharmacy of Agadir, Souss-Massa University Hospital, Ibn Zohr University, Agadir, Morocco., Adarmouch L; Clinical Research Department, Mohammed VI University Hospital, Marrakesh, Morocco.; Community Medicine and Public Health Department, Bioscience and Health Research Laboratory, School of Medicine, Cadi Ayyad University, Marrakesh, Morocco., Serhane H; Pneumology Department, Faculty of Medicine and Pharmacy of Agadir, Souss-Massa University Hospital, Ibn Zohr University, Agadir, Morocco. |
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| Jazyk: | angličtina |
| Zdroj: | Nigerian medical journal : journal of the Nigeria Medical Association [Niger Med J] 2024 Apr 21; Vol. 65 (1), pp. 56-66. Date of Electronic Publication: 2024 Apr 21 (Print Publication: 2024). |
| DOI: | 10.60787/nmj-v65i1-451 |
| Abstrakt: | Background: Different studies have identified the prognostic factors of COVID-19 infection. These studies have revealed that COVID-19 infection is more severe in males than in females. The aim of our study was to compare the severity of COVID-19 infection between males and females in terms of clinical, biological, radiological, and evolutionary aspects. Methodology: This is a cross-sectional observational study conducted in patients hospitalized with COVID-19 infection over a 6-month period from 1 August 2021 to 1 February 2022. Results: The comparison of clinical, biological, radiological, and evolutionary severity factors of covid-19 infection between the two sexes revealed that this infection was more severe in males. Statistically significant differences were noted for the rate of high dimers (p =0.01) and for lung involvement greater than 25% on chest CT (Computed tomography) (p =0.008). Conclusion: The severity of covid-19 infection in men is due to biological differences between men and women in the renin-angiotensin system, the immune system, genetics, and sex hormones. Further research into the pathophysiological mechanisms behind this finding is needed. Competing Interests: There are no conflicts of interest. (Copyright © 2024 Nigerian Medical Association.) |
| Databáze: | MEDLINE |
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