Clinical signs associated with severe ST segment elevation in three cats with a hypertrophic cardiomyopathy phenotype.

Autor: Seo J; Animal Referral Centre (ARC Central), 8 Hereford Street, Freemans Bay, Auckland 1011, New Zealand; School of Veterinary Science, Massey University, Tennent Drive, Palmerston North 4410, New Zealand. Electronic address: s.joonbm@gmail.com., Kurosawa TA; Dick White Referrals, Station Farm, London Road, Six Mile Bottom, Cambridgeshire CB8 0UH, United Kingdom., Borgeat K; Eastcott Veterinary Referral, Edison Park, Hindle Way, Dorcan Way, Swindon SN3 3FR, United Kingdom., Novo Matos J; Department of Veterinary Medicine, University of Cambridge, Madingley Rd, Cambridge CB3 0ES, United Kingdom., Hutchinson JC; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, United Kingdom., Arthurs OJ; Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, United Kingdom., Luis Fuentes V; Department of Clinical Science and Services, The Royal Veterinary College, Hawkshead Ln, Brookmans Park, Hatfield AL9 7TA, United Kingdom.
Jazyk: angličtina
Zdroj: Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology [J Vet Cardiol] 2024 Aug; Vol. 54, pp. 30-37. Date of Electronic Publication: 2024 Jun 22.
DOI: 10.1016/j.jvc.2024.05.003
Abstrakt: Three cats were presented for unusual collapsing episodes. Echocardiography revealed a hypertrophic cardiomyopathy (HCM) phenotype in each cat. Continuous electrocardiographic monitoring showed that the clinical signs coincided with periods of severe ST-segment elevation in each cat. The first cat was treated with amlodipine and diltiazem but did not improve and was euthanized due to poor quality of life. Postmortem examination revealed cardiac lymphoma without obstructive coronary disease. The second cat was thought to have cardiac lymphoma, based on pericardial effusion cytology, and was euthanized before starting therapy. The third cat was diagnosed with HCM and left ventricular outflow tract obstruction and was treated with atenolol and diltiazem. This treatment reduced the frequency of episodic clinical signs, but the cat subsequently developed congestive heart failure and was euthanized. This case series describes clinical signs associated with severe ST elevation in cats with an HCM phenotype, and their outcomes. Continuous electrocardiographic monitoring was necessary to detect transient ST elevation in each case.
Competing Interests: Conflict of Interest Statement The authors do not have any conflict of interest to disclose.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE