Autor: |
Tanasic V; University of Belgrade, Faculty of Biology, Center for Forensic and Applied Molecular Genetics, Studentski trg 16, 11000 Belgrade, Serbia., Vukovic M; University of Belgrade, Faculty of Biology, Center for Forensic and Applied Molecular Genetics, Studentski trg 16, 11000 Belgrade, Serbia., Mihajlovic Srejic M; University of Belgrade, Faculty of Biology, Center for Forensic and Applied Molecular Genetics, Studentski trg 16, 11000 Belgrade, Serbia., Kecmanovic M; University of Belgrade, Faculty of Biology, Center for Forensic and Applied Molecular Genetics, Studentski trg 16, 11000 Belgrade, Serbia., Keckarevic Markovic M; University of Belgrade, Faculty of Biology, Center for Forensic and Applied Molecular Genetics, Studentski trg 16, 11000 Belgrade, Serbia, milica@bio.bg.ac.rs., Keckarevic D; University of Belgrade, Faculty of Biology, Center for Forensic and Applied Molecular Genetics, Studentski trg 16, 11000 Belgrade, Serbia. |
Abstrakt: |
Genetic variability of Roma population was shaped by the strong influence of genetic drift and gene flow during the migrations from their ancestral homeland in Indian subcontinent towards Europe. In addition, social stigmatization in many European countries, as a consequence of different cultural heritage and social practices, induced further genetic differentiation and sub structuring within the population. Although many populations genetic studies on European Roma were carried out, the genetic structure of the Serbian Roma has not been described yet, since only the modest number of individuals from this territory was analyzed. The main aim of this study was the characterization of genetic variability of the Roma and the assessment of intrapopulation genetic differentiation based on the analysis of 21 autosomal STR loci of 259 self-identified unrelated individuals from Serbia. Intrapopulation analysis revealed divergence of Roma groups illustrating the effect of the historical events after their arrival on Balkan Peninsula and emphasizing significance of the religious affiliation on admixture with autochthonous population. Genetic distance analysis showed the greatest similarity of the studied population with the Middle Eastern populations, while South Asian and European population were more distant. Our results demonstrate that Roma groups in this region of Balkan Peninsula do not represent completely isolated, but rather admixed populations with different proportion of gene flow with other Roma and non-Roma groups. |