Nuclear protein in testis (NUT) midline carcinoma of the larynx: A rare case report of a paediatric patient and literature review.

Autor: Ugurluer G; Department of Radiation Oncology, Acibadem MAA University School of Medicine, Istanbul, Turkey., Dincer N; Department of Radiation Oncology, Acibadem MAA University School of Medicine, Istanbul, Turkey., Danyeli AE; Division of Neuropathology, Department of Pathology, Acibadem University School of Medicine, Istanbul, Turkey., Celik L; Department of Radiology, Acibadem Maslak Hospital, Istanbul, Turkey., Guner AL; Department of Nuclear Medicine, Acıbadem Mehmet Ali Aydinlar University Faculty of Medicine, Istanbul, Turkey., Corapcioglu F; Division of Hematology and Oncology, Department of Paediatrics, Acibadem Maslak Hospital, Istanbul, Turkey., Canpolat C; Division of Hematology and Oncology, Department of Paediatrics, Acibadem University School of Medicine, Istanbul, Turkey., Kok YB; Department of Pathology, Acibadem University School of Medicine, Istanbul, Turkey., Ozyar E; Department of Radiation Oncology, Acibadem MAA University School of Medicine, Istanbul, Turkey. Electronic address: enis.ozyar@acibadem.com.
Jazyk: angličtina
Zdroj: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2024 Aug; Vol. 28 (4), pp. 385-389. Date of Electronic Publication: 2024 Jul 14.
DOI: 10.1016/j.canrad.2024.02.004
Abstrakt: Nuclear protein in testis (NUT) carcinoma is a rare neoplasm arising mainly from midline structures. It is an aggressive type of carcinoma associated with poor survival despite the use of multiple treatment modalities. Here, we present a case of a 17-year-old paediatric patient with NUT carcinoma of larynx, which is even rarer among all reported cases. The patient underwent surgery followed by radiotherapy and systemic treatment and he died 15 months after the diagnosis. The management of this rare disease requires further investigation.
(Copyright © 2024 Société française de radiothérapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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