Percarbonate mediated advanced oxidation of irbesartan: A suitable alternative to chlorination?

Autor: Medici A; Department of Chemical Sciences, University of Naples Federico II, Via Vicinale Cupa Cintia 26, 80126 Naples, Italy. Electronic address: antonio.medici@unina.it., Siciliano A; Department of Biology, University of Naples Federico II, Via Vicinale Cupa Cintia 21, 80126 Naples, Italy. Electronic address: antonietta.siciliano@unina.it., Libralato G; Department of Biology, University of Naples Federico II, Via Vicinale Cupa Cintia 21, 80126 Naples, Italy. Electronic address: giovanni.libralato@unina.it., Saviano L; Department of Biology, University of Naples Federico II, Via Vicinale Cupa Cintia 21, 80126 Naples, Italy., Guida M; Department of Biology, University of Naples Federico II, Via Vicinale Cupa Cintia 21, 80126 Naples, Italy. Electronic address: marco.guida@unina.it., Pedatella S; Department of Chemical Sciences, University of Naples Federico II, Via Vicinale Cupa Cintia 26, 80126 Naples, Italy. Electronic address: silvana.pedatella@unina.it., Luongo G; Associazione Italiana per la Promozione delle Ricerche su Ambiente e Salute umana, Via Campellone 50, 82030 Dugenta, BN, Italy. Electronic address: giovanni.luongo@unina.it., Di Fabio G; Department of Chemical Sciences, University of Naples Federico II, Via Vicinale Cupa Cintia 26, 80126 Naples, Italy. Electronic address: difabio@unina.it., Zarrelli A; Department of Chemical Sciences, University of Naples Federico II, Via Vicinale Cupa Cintia 26, 80126 Naples, Italy. Electronic address: zarrelli@unina.it.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2024 Oct 15; Vol. 947, pp. 174730. Date of Electronic Publication: 2024 Jul 16.
DOI: 10.1016/j.scitotenv.2024.174730
Abstrakt: This study aims to investigate the environmental fate of irbesartan when subjected to activated percarbonate treatment. The investigation delves into the formation of disinfection byproducts (DBPs) and evaluates their toxicity, and it seeks to draw comparisons with outcomes from treatment with sodium hypochlorite, already characterized in previous findings. The proposed treatment indicates the formation of at least 11 DBPs - eight identified for the first time - which have been isolated by various chromatographic techniques, identified by Nuclear Magnetic Resonance and Mass Spectrometry studies and for which a mechanism has been proposed to elucidate their formation. To evaluate irbesartan's biological impact during treatment with sodium percarbonate (SPC), a toxicity study of the DBPs was conducted using Daphnia magna, Aliivibrio fischeri, and Raphidocelis subcapitata, three model organisms. The ecotoxicity was evaluated using the Ecological Structure-Activity Relationships (ECOSAR) computer program and compared with experimental results. Compared to chlorination treatment, a lower mineralization percentage (-43 %) and amount of DBPs at least twice higher were observed. Toxicity assessment highlighted that DBPs formed during SPC treatment were more toxic than those from chlorination. ECOSAR predicted toxicity aligned with experimental findings. Additionally, the DBPs exhibited varying levels of toxicity, primarily attributable to the presence of aromatic and hydroxyl groups in their chemical structure, indicating that SPC treatment is not suitable for treatment of irbesartan polluted waters.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: