Multiparametric Prostate MRI Accuracy of Prostate Imaging Reporting and Data System (v2.1) Scores 4 and 5: The Influence of Image Quality According to the Prostate Imaging Quality Score.

Autor: Fuschi A; Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Suraci PP; Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Pastore AL; Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Al Salhi Y; Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Capodiferro P; Department of Radiological, Oncological and Pathological Sciences, Academic Diagnostic, Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Scalzo S; Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Rera OA; Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Valenzi FM; Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Di Dio M; Division of Urology, Department of Surgery, Annunziata Hospital, 87100 Cosenza, Italy., Russo P; Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.; Urology Unit, Fondazione Policlinico A. Gemelli IRCCS, Largo Agostino Gemelli 8, 00168 Rome, Italy., Al-Zubi MT; Department of Surgery, Division of Urology, School of Medicine, Yarmouk University, Irbid 21110, Jordan., Al Demour S; Department of Special Surgery, Division of Urology, School of Medicine, The University of Jordan, Amman 11972, Jordan., Fathi Al-Rawashdah S; Department of Special Surgery, Urology Unit, School of Medicine, Mutah University, Karak 61710, Jordan., Mazzon G; Institute of Urology, University College Hospital, London NW12BU, UK., Bellini D; Department of Radiological, Oncological and Pathological Sciences, Academic Diagnostic, Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Carbone I; Department of Radiological, Oncological and Pathological Sciences, Academic Diagnostic, Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Petrozza V; Pathology Unit, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Bozzini G; Division of Urology, Sant'Anna Hospital, San Fermo della Battaglia, 22042 Como, Italy., Zucchi A; Department of Urology, University of Pisa, 56126 Pisa, Italy., Pacini M; Department of Urology, University of Pisa, 56126 Pisa, Italy., Tema G; Department of Urology, Sapienza University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy., De Nunzio C; Department of Urology, Sapienza University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy., Carbone A; Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy., Rengo M; Department of Radiological, Oncological and Pathological Sciences, Academic Diagnostic, Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2024 Jun 27; Vol. 13 (13). Date of Electronic Publication: 2024 Jun 27.
DOI: 10.3390/jcm13133785
Abstrakt: Purpose: The accuracy of multiparametric magnetic resonance imaging (mpMRI) heavily relies on image quality, as evidenced by the evolution of the prostate imaging quality (PI-QUAL) scoring system for the evaluation of clinically significant prostate cancer (csPC). This study aims to evaluate the impact of PI-QUAL scores in detecting csPC within PI-RADS 4 and 5 lesions. Methods: We retrospectively selected from our database all mpMRI performed from January 2019 to March 2022. Inclusion criteria were as follows: (1) mpMRI acquired in our institution according to the technical requirements from the PI-RADS (v2.1) guidelines; (2) single lesion scored as PI-RADS (v2.1) 4 or 5; (3) MRI-TBx performed in our institution; (4) complete histology report; and (5) complete clinical record. Results: A total of 257 male patients, mean age 70.42 ± 7.6 years, with a single PI-RADS 4 or 5 lesion undergoing MRI-targeted biopsy, were retrospectively studied. Of these, 61.5% were PI-RADS 4, and 38.5% were PI-RADS 5, with 84% confirming neoplastic cells. In high-quality image lesions (PI-QUAL ≥ 4), all PI-RADS 5 lesions were accurately identified as positive at the final histological examination (100% of CDR). For PI-RADS 4 lesions, 37 (23%) were negative, resulting in a cancer detection rate of 77% (95% CI: 67.51-84.83). Conclusions: The accuracy of mpMRI, independently of the PI-RADS score, progressively decreased according to the decreasing PI-QUAL score. These findings emphasize the crucial role of the PI-QUAL scoring system in evaluating PI-RADS 4 and 5 lesions, influencing mpMRI accuracy.
Databáze: MEDLINE