Evaluating Postoperative Prognosis: A Single Surgeon's Experience With Total Mesorectal Excision in Middle and Lower Rectal Cancer Cases in Iraq.

Autor:	Mahmood AS; Department of Surgery, College of Medicine, University of Baghdad, Baghdad, IRQ., Ahmed Abbas M; Department of Surgery, College of Medicine, University of Baghdad, Baghdad, IRQ., Gany Yassin A; Department of Biochemistry, College of Medicine, University of Karbala, Karbala, IRQ., Ahmed HA; Department of Surgery, Iraqi Board of Medical Specializations, Baghdad, IRQ., Sabri S; Department of Surgery, Baghdad Teaching Hospital, Baghdad, IRQ., Shakir AA; Department of Surgery, Baghdad Teaching Hospital, Baghdad, IRQ., Abbas H; Department of Surgery, College of Medicine, University of Baghdad, Baghdad, IRQ., Ismail M; Department of Surgery, College of Medicine, University of Baghdad, Baghdad, IRQ.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jun 11; Vol. 16 (6), pp. e62174. Date of Electronic Publication: 2024 Jun 11 (Print Publication: 2024).
DOI:	10.7759/cureus.62174
Abstrakt:	Introduction: Surgical intervention for rectal cancer is widely recognized for its potential to significantly impact quality of life, chiefly due to the high probability of permanent colostomy and the associated postoperative complications. Objective: This study aimed to evaluate the short-term outcomes and morbidity associated with total mesorectal excision for middle and lower rectal cancer within an Iraqi cohort, in a prospective setting. Methods: This study prospectively collected and analyzed data from 89 patients who underwent a standardized radical rectal resection, with a follow-up period extending to one month post-surgery. Results: The mean age of patients was 54.4 ± 12.9 years, with a gender distribution of 46 males and 43 females. A total of 33 patients presented with preoperative comorbidities, which heightened the risk of adverse short-term outcomes by a factor of 7.51. The most prevalent comorbidities were hypertension and diabetes mellitus, affecting 22 and 20 patients, respectively. Patients aged 60 years and above were at a 3.97 times greater risk of developing complications. The overall complication rate was 21.35%, with wound infections (9.0%) and cardiovascular events (3.4%) being the most common. Mortality during the follow-up was 1.1%. Conclusion: The findings indicate that increased age and the presence of comorbidities are significant risk factors for morbidity and mortality post-surgery. Neoadjuvant chemoradiotherapy or radiotherapy was shown to reduce morbidity and mortality rates while improving survival. The morbidity and mortality rates observed in this study concur with existing literature. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Iraqi Board of Medical Specializations issued approval 916. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Mahmood et al.)
Databáze:	MEDLINE
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