A Unique Case of Intracranial Bifocal Germinoma.

Autor: Chetana Naga Sai T; Radiology, Nizam's Institute of Medical Sciences, Hyderabad, IND., Narayanan R; Radiology, Nizam's Institute of Medical Sciences, Hyderabad, IND., Uppin MS; Pathology, Nizam's Institute of Medical Sciences, Hyderabad, IND., Kanala RR; Neurological Surgery, Nizam's Institute of Medical Sciences, Hyderabad, IND.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Jun 11; Vol. 16 (6), pp. e62167. Date of Electronic Publication: 2024 Jun 11 (Print Publication: 2024).
DOI: 10.7759/cureus.62167
Abstrakt: Primary intracranial germ cell tumors are rare tumors that often occur in children and young adults. We report a case of a 17-year-old male, who presented with vomiting, headache, and blurring of vision of the left eye on the temporal aspect for two months. His biological assessment showed panhypopituitarism. Serum markers showed elevated beta human chorionic gonadotropin and lactate dehydrogenase. A solid cystic lesion was noted on imaging, involving the sella, parasellar region, and pineal region with calcifications within. Diagnosis of bifocal germinoma was confirmed by tumor biopsy. The treatment protocol for the patient involved four cycles of chemotherapy using etoposide and carboplatin, followed by a course of radiotherapy.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Chetana Naga Sai et al.)
Databáze: MEDLINE