Prevalence and characteristics of chronic kidney disease in people with type 2 diabetes mellitus in the Autonomous Community of Aragon.

Autor: Sánchez-Calavera MA; Health Service of Aragon, Spain; Instituto de Investigación Sanitaria de Aragón (IISA, Aragon Health Research Institute), Spain; Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Navarro RG; Health Service of Aragon, Spain; Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain. Electronic address: rgomezn@salud.aragon.es., Otal EA; Health Service of Aragon, Spain; Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., González IB; Health Service of Aragon, Spain; Instituto de Investigación Sanitaria de Aragón (IISA, Aragon Health Research Institute), Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Pardo DE; Health Service of Aragon, Spain; Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Celma LH; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Lamarre M; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Esteban PL; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Lozano Del Hoyo ML; Health Service of Aragon, Spain; Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Mahulea L; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Gallego IM; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain; Sociedad Española de Farmacia Clínica, Familiar y Comunitaria (Spanish Society of Clinical, Family and Community Pharmacy), Spain., Romero-Vigara JC; Health Service of Aragon, Spain; Instituto de Investigación Sanitaria de Aragón (IISA, Aragon Health Research Institute), Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Allué SS; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Hueso ST; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Gil FA; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain.
Jazyk: angličtina
Zdroj: Primary care diabetes [Prim Care Diabetes] 2024 Oct; Vol. 18 (5), pp. 555-560. Date of Electronic Publication: 2024 Jul 10.
DOI: 10.1016/j.pcd.2024.06.006
Abstrakt: Aims: The main objective in this study was to determine the prevalence of Chronic Kidney Disease (CKD) in people with Type 2 Diabetes Mellitus (T2DM) in the Autonomous Community (AC) of Aragon (Spain) and to detect whether or not there is under-registration in the patient's history. As a secundary objetive, it was proposed to study the most relevant demographic and clinical characteristics of people with CKD.
Methods: Observational and retrospective real world data study of the population over 18 years of age with a diagnosis of T2DM, between January 2017 and December 2021. A descriptive analysis of qualitative and quantitative variables, and a comparison using the parametric Student's t-test or the non-parametric Mann-Whitney U-test between both groups was performed.
Results: The prevalence of T2DM was 8.07 % and that of CKD 31.4 %, with an under-reporting of 47 %. The main risk factor associated with CKD was arterial hypertension (p<0.001), followed by dyslipidemia (p<0.001). The main treatment used for diabetes control was metformin, both in patients with and without CKD (p<0.001). A total of 56.81 % of people with T2DM and CKD did not undergo annual monitoring of their renal function (glomerular filtration rate) or determination of albuminuria.
Conclusions: The prevalence of CKD increases in patients with T2DM (31.4 %), and in almost half of patients the diagnosis is not registered (47 %). This under-reporting delays the implementation of measures needed to prevent CKD progression.
Competing Interests: Declaration of Competing Interest The authors declare no conflict of interest in the conduct of this study.
(Copyright © 2024 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE