Impact of Bariatric Surgery on Asthma Severity and Medication Use.

Autor: Smith BM; Department of Surgery, Gundersen Health System, 1900 South Avenue, La Crosse Clinic - Level 5, La Crosse, WI, 54601, USA., Fitzsimmons AJ; Department of Surgery, Gundersen Health System, 1900 South Avenue, La Crosse Clinic - Level 5, La Crosse, WI, 54601, USA., Kovacs AJ; Department of Surgery, Gundersen Health System, 1900 South Avenue, La Crosse Clinic - Level 5, La Crosse, WI, 54601, USA., Grover BT; Department of Surgery, Gundersen Health System, 1900 South Avenue, La Crosse Clinic - Level 5, La Crosse, WI, 54601, USA., Pfeiffer JD; Department of Surgery, Gundersen Health System, 1900 South Avenue, La Crosse Clinic - Level 5, La Crosse, WI, 54601, USA. jdpeiff@gundersenhealth.org.
Jazyk: angličtina
Zdroj: Obesity surgery [Obes Surg] 2024 Aug; Vol. 34 (8), pp. 2814-2819. Date of Electronic Publication: 2024 Jul 11.
DOI: 10.1007/s11695-024-07074-y
Abstrakt: Introduction: Bariatric surgery improves many obesity-related comorbidities, yet the literature remains inconclusive on the impact of bariatric surgery on asthma. Our primary objective was to identify the long-term impact of bariatric surgery on asthma severity and medication use.
Methods: A retrospective review was completed of all patients with a diagnosis of asthma who underwent bariatric surgery over 10 years at a single institution. Primary outcomes were the number of asthma medications prescribed at five time points (preoperative, postoperative < 18 months, 19-36 months, 37-60 months, 60 + months) after bariatric surgery. Secondary outcomes were spirometry results and BMI.
Results: There were 260 patients with 84.6% female predominance. There were 168 sleeve gastrectomy patients and 92 Roux-en-Y gastric bypass patients. Mean age was 47.6 ± 10.7 years, mean BMI was 46.0 ± 6.8 kg/m 2 , and 54.2% were previous tobacco users. The total number of patients on two or more asthma medications decreased from 46% preoperatively to 41% at 18 months, to 36% at 36 months, and to 32% at 60 months after surgery. The total number of patients free from asthma medication increased from 25% preoperatively to 33% at 60 months postoperatively. Asthma medication use decreased in both surgery groups, and neither operation demonstrated superiority. No significant improvement nor differences were found between groups at any time point regarding FEV 1 /FVC ratio spirometry measures.
Conclusion: Bariatric surgery reduces the use of medications taken for management of asthma. The amount of asthma medication usage decreases with time and is sustained at 60 months after bariatric surgery.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE