Clinical and electroencephalographic correlates of carbamazepine-associated hiccups in epileptic patients.
| Autor: | Elendu C; Federal University Teaching Hospital, Owerri, Nigeria., Jeswani BM; GCS Medical College, Hospital & Research Centre, Ahmedabad, Gujarat, India., Madekwe CC; Vinnytsia National Medical University, Vinnytsia., Chukwuneta CP; Chukwuemeka Odumegwu Ojukwu University, Anambra., Sidhu AK; Kharkiv National Medical University Kharkiv, Ukraine., Okorie CO; Croydon University Hospital, London, UK., Banerjee AV; College of Basic Medical Sciences of Jilin University, Changchun, China., Oshin BD; Babcock University Ilishan-Remo, Ogun State, Nigeria. |
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| Jazyk: | angličtina |
| Zdroj: | Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2024 May 15; Vol. 86 (7), pp. 4015-4034. Date of Electronic Publication: 2024 May 15 (Print Publication: 2024). |
| DOI: | 10.1097/MS9.0000000000002159 |
| Abstrakt: | Carbamazepine, a commonly prescribed antiepileptic drug, is known to induce hiccups in a subset of epileptic patients. Although relatively uncommon, can have significant clinical implications. This comprehensive review delves into the clinical and electroencephalographic correlates of carbamazepine-associated hiccups, aiming to enhance understanding and management of this neurological side effect. The authors' review synthesizes qualitative epidemiological data, revealing that carbamazepine-induced hiccups occur in a subset of patients receiving the medication, with reported incidence rates ranging from 2.5 to 40%. Despite its relatively low prevalence, hiccups pose substantial challenges for patients and healthcare providers. Complications associated with carbamazepine-induced hiccups include disruption of sleep, impaired social functioning, and decreased quality of life, underscoring the clinical significance of this side effect. Effective management strategies can be implemented through a multidisciplinary approach, including collaboration among neurologists, pharmacists, and other healthcare professionals. These may include dose adjustments, medication discontinuation, and adjunctive therapies such as diaphragmatic breathing exercises or acupuncture. Additionally, close monitoring for adverse effects and timely intervention are essential to mitigate the impact of hiccups on patient well-being. Essentially, carbamazepine-induced hiccups represent a clinically relevant phenomenon that warrants attention in the management of epilepsy. By recognizing the clinical manifestations, understanding the underlying pathophysiology, and implementing evidence-based management strategies, healthcare providers can optimize patient care and improve outcomes in this patient population. Competing Interests: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.) |
| Databáze: | MEDLINE |
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