A Diagnosis of Gastric Inflammatory Myofibroblast Tumor: A Challenge Like No Other!

Autor: Chukkalore D; Department of Internal Medicine, Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital, Staten Island, NY., Loeffler J; Department of Internal Medicine, Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital, Staten Island, NY., Rabah H; Department of Internal Medicine, Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital, Staten Island, NY., Amarnath S; Department of Gastroenterology & Hepatology, Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital, Staten Island, NY., Al Moussawi H; Department of Gastroenterology & Hepatology, Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital, Staten Island, NY., Deeb L; Department of Gastroenterology & Hepatology, Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital, Staten Island, NY.
Jazyk: angličtina
Zdroj: ACG case reports journal [ACG Case Rep J] 2024 Jul 10; Vol. 11 (7), pp. e01416. Date of Electronic Publication: 2024 Jul 10 (Print Publication: 2024).
DOI: 10.14309/crj.0000000000001416
Abstrakt: Inflammatory myofibroblastic tumors (IMTs) are mesenchymal tumors of intermediate malignant potential. Gastric IMTs are rare and commonly affect young adults. They are typically confused with gastrointestinal stromal tumors, inflammatory fibroid polyps, and leiomyosarcomas. The etiology of IMTs remains unclear, but is theorized to be due to hyperinflammatory response to chronic infections. We present a middle-aged woman found to have a gastric mass positive for Helicobacter pylori , underwent multiple endoscopies with endoscopic ultrasound, and a definitive diagnosis of gastric IMT was only made after a partial gastrectomy with immunohistochemistry negative for CD-117, S-100, ALK-1, and positive for vimentin and SMA.
(© 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.)
Databáze: MEDLINE