Inhibitory control of gait initiation in humans: An electroencephalography study.

Autor: Ziri D; Sorbonne Université, Institut du Cerveau - Paris Brain Institute, Inserm, CNRS, AP-HP, Hôpital de la Pitié Salpêtrière, Paris, France., Hugueville L; Sorbonne Université, Institut du Cerveau - Paris Brain Institute, Inserm, CNRS, AP-HP, Hôpital de la Pitié Salpêtrière, Paris, France.; Institut du Cerveau, ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, Centre MEG-EEG, CENIR, Paris, France., Olivier C; Sorbonne Université, Institut du Cerveau - Paris Brain Institute, Inserm, CNRS, AP-HP, Hôpital de la Pitié Salpêtrière, Paris, France.; PANAM Core Facility, CENIR, Paris Brain Institute, Paris, France., Boulinguez P; INSERM, CNRS, Lyon Neuroscience Research Center, Université de Lyon, Lyon, France., Gunasekaran H; Sorbonne Université, Institut du Cerveau - Paris Brain Institute, Inserm, CNRS, AP-HP, Hôpital de la Pitié Salpêtrière, Paris, France., Lau B; Sorbonne Université, Institut du Cerveau - Paris Brain Institute, Inserm, CNRS, AP-HP, Hôpital de la Pitié Salpêtrière, Paris, France., Welter ML; Sorbonne Université, Institut du Cerveau - Paris Brain Institute, Inserm, CNRS, AP-HP, Hôpital de la Pitié Salpêtrière, Paris, France.; Institut du Cerveau, ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, Centre MEG-EEG, CENIR, Paris, France.; Department of Neurophysiology, Rouen University Hospital and University of Rouen, Rouen, France., George N; Sorbonne Université, Institut du Cerveau - Paris Brain Institute, Inserm, CNRS, AP-HP, Hôpital de la Pitié Salpêtrière, Paris, France.; Institut du Cerveau, ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, Centre MEG-EEG, CENIR, Paris, France.
Jazyk: angličtina
Zdroj: Psychophysiology [Psychophysiology] 2024 Nov; Vol. 61 (11), pp. e14647. Date of Electronic Publication: 2024 Jul 10.
DOI: 10.1111/psyp.14647
Abstrakt: Response inhibition is a crucial component of executive control. Although mainly studied in upper limb tasks, it is fully implicated in gait initiation. Here, we assessed the influence of proactive and reactive inhibitory control during gait initiation in healthy adult participants. For this purpose, we measured kinematics and electroencephalography (EEG) activity (event-related potential [ERP] and time-frequency data) during a modified Go/NoGo gait initiation task in 23 healthy adults. The task comprised Go-certain, Go-uncertain, and NoGo conditions. Each trial included preparatory and imperative stimuli. Our results showed that go-uncertainty resulted in delayed reaction time, without any difference for the other parameters of gait initiation. Proactive inhibition, that is, Go uncertain versus Go certain conditions, influenced EEG activity as soon as the preparatory stimulus. Moreover, both proactive and reactive inhibition influenced the amplitude of the ERPs (central P1, occipito-parietal N1, and N2/P3) and theta and alpha/low beta band activities in response to the imperative-Go-uncertain versus Go-certain and NoGo versus Go-uncertain-stimuli. These findings demonstrate that the uncertainty context; induced proactive inhibition, as reflected in delayed gait initiation. Proactive and reactive inhibition elicited extended and overlapping modulations of ERP and time-frequency activities. This study shows the protracted influence of inhibitory control in gait initiation.
(© 2024 The Author(s). Psychophysiology published by Wiley Periodicals LLC on behalf of Society for Psychophysiological Research.)
Databáze: MEDLINE
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