SBRT for Pancreatic Cancer: A Radiosurgery Society Case-Based Practical Guidelines to Challenging Cases.

Autor: Liu J; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, California. Electronic address: jaliu@coh.org., Sidiqi B; Department of Radiation Oncology, Northwell Health Cancer Institute, New Hyde Park, New York., McComas K; Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennesse., Gogineni E; Department of Radiation Oncology, Ohio State James Cancer Center, Columbus, Ohio., Andraos T; Department of Radiation Oncology, Ohio State James Cancer Center, Columbus, Ohio., Crane CH; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York City, New York., Chang DT; Department of Radiation Oncology, University of Michigan Health, Ann Arbor, Michigan., Goodman KA; Department of Radiation Oncology, Mount Sinai Health, New York City, New York., Hall WA; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin., Hoffe S; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida., Mahadevan A; Department of Radiation Oncology, NYU Langone Health, New York City, New York., Narang AK; Department of Radiation Oncology, Johns Hopkins University Kimmel Cancer Center, Baltimore, Maryland., Lee P; Department of Radiation Oncology, City of Hope Lennar Cancer Center, Irvine, California., Williams TM; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, California., Chuong MD; Department of Radiation Oncology, Baptist Health South Florida, Miami, Florida.
Jazyk: angličtina
Zdroj: Practical radiation oncology [Pract Radiat Oncol] 2024 Nov-Dec; Vol. 14 (6), pp. 555-573. Date of Electronic Publication: 2024 Jul 08.
DOI: 10.1016/j.prro.2024.06.004
Abstrakt: The use of radiation therapy (RT) for pancreatic cancer continues to be controversial, despite recent technical advances. Improvements in systemic control have created an evolving role for RT and the need for improved local tumor control, but currently, no standardized approach exists. Advances in stereotactic body RT, motion management, real-time image guidance, and adaptive therapy have renewed hopes of improved outcomes in this devastating disease with one of the lowest survival rates. This case-based guide provides a practical framework for delivering stereotactic body RT for locally advanced pancreatic cancer. In conjunction with multidisciplinary care, an intradisciplinary approach should guide treatment of the high-risk cases outlined within these guidelines for prospective peer review and treatment safety discussions.
Competing Interests: Disclosures Christopher H. Crane receives consulting fees from Trisalis and honoraria from Elekta and has stock options in Oncternal. Karyn A. Goodman serves on the advisory board of RenovoRx and leadership in the NCI GI Steering Committee. Percy Lee receives consulting fees from Varian, ViewRay, AstraZeneca, Genentech, Johnson & Johnson, RTOG Foundation, honoraria from Varian, ViewRay, AstraZeneca, and travel support from Radiosurgery Society; serves on the advisory board for Genentech, ViewRay, AstraZeneca, Roche, and leadership of Radiosurgery Society, ASTRO. Michael D. Chuong receives grants, consulting fees, honoraria, and travel support from ViewRay, and serves on the advisory board of ViewRay.
(Copyright © 2024 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE