Cost of lost productivity in inflammatory arthritis and osteoarthritis in the year before and after diagnosis: An inception cohort study.

Autor: Xiang L; Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Graves N; Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore., Low AHL; Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Leung YY; Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Fong W; Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Gan WH; Duke-NUS Medical School, Singapore, Singapore.; Department of Occupational and Environmental Medicine, Singapore General Hospital, Singapore, Singapore., Gandhi M; Biostatistics, Singapore Clinical Research Institute, Singapore, Singapore.; Centre of Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.; Tampere Center for Child Health Research, Tampere University, Tampere, Finland., Thumboo J; Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Jazyk: angličtina
Zdroj: International journal of rheumatic diseases [Int J Rheum Dis] 2024 Jul; Vol. 27 (7), pp. e15252.
DOI: 10.1111/1756-185X.15252
Abstrakt: Aim: Existing studies on the cost of inflammatory arthritis (IA) and osteoarthritis (OA) are often cross-sectional and/or involve patients with various disease durations, thus not providing a comprehensive perspective on the cost of illness from the time of diagnosis. In this study, we therefore assessed the cost of lost productivity in an inception cohort of patients with IA and OA in the year before and after diagnosis.
Methods: Employment status, monthly income, days absent from work, and presenteeism were collected at diagnosis and 1 year later to estimate the annual costs of unemployment, absenteeism, and presenteeism using human capital approach. Non-parametric bootstrapping was performed to account for the uncertainty of the estimated costs.
Results: Compared to patients with OA (n = 64), patients with IA (n = 102, including 48 rheumatoid arthritis, 19 spondyloarthritis, 23 psoriatic arthritis, and 12 seronegative IA patients) were younger (mean age: 52.3 vs. 59.5 years) with a greater proportion receiving treatment (99.0% vs. 67.2%) and a greater decrease in presenteeism score (median: 15% vs 10%) 1 year after diagnosis. Annual costs of absenteeism and presenteeism were lower in patients with IA than those with OA both in the year before (USD566 vs. USD733 and USD8,472 vs. USD10,684, respectively) and after diagnosis (USD636 vs. USD1,035 and USD6,866 vs. USD9,362, respectively).
Conclusion: Both IA and OA impose substantial cost of lost productivity in the year before and after diagnosis. The greater improvement in productivity seen in patients with IA suggests that treatment for IA improves work productivity.
(© 2024 The Author(s). International Journal of Rheumatic Diseases published by Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.)
Databáze: MEDLINE
Externí odkaz: