Birth Outcomes Related to Prenatal Zika, Dengue, and Other Flavivirus Infections in the Zika en Embarazadas y Niños Prospective Cohort Study in Colombia.

Autor: Tannis A; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia.; Eagle Global Scientific, LLC, San Antonio, Texas., Newton S; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia., Rico A; Division of Research in Public Health, National Institute of Health, Bogota, Colombia., Gonzalez M; Division of Research in Public Health, National Institute of Health, Bogota, Colombia., Benavides M; Maternal and Perinatal Research Division, National Institute of Health, Bogota, Colombia., Ricaldi JN; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Rodriguez H; Division of Research in Public Health, National Institute of Health, Bogota, Colombia., Zambrano LD; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Daza M; Maternal and Perinatal Research Division, National Institute of Health, Bogota, Colombia., Godfred-Cato S; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia., Thomas JD; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Acosta J; Research Division, Vysnova Partners, Bethesda, Maryland., Maniatis P; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Daniels JB; Office of Readiness and Response, Centers for Disease Control and Prevention, Atlanta, Georgia., Burkel V; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia.; Eagle Global Scientific, LLC, San Antonio, Texas., Ailes EC; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia., Valencia D; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Gilboa SM; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia., Jamieson DJ; Carver College of Medicine, University of Iowa, Iowa City, Iowa., Mercado M; Maternal and Perinatal Research Division, National Institute of Health, Bogota, Colombia., Villanueva JM; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Honein MA; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Ospina ML; Global Health Department, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, Florida.; Department of Health Sciences, Simon Boliviar University, Bogota, Colombia., Tong VT; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia.
Jazyk: angličtina
Zdroj: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2024 Jul 09; Vol. 111 (3), pp. 622-626. Date of Electronic Publication: 2024 Jul 09 (Print Publication: 2024).
DOI: 10.4269/ajtmh.23-0873
Abstrakt: Zika virus (ZIKV) infection in pregnancy is associated with severe abnormalities of the brain and eye and other adverse outcomes. Zika en Embarazadas y Niños was a prospective cohort study conducted in multiple Colombian cities that enrolled pregnant women in their first trimester. Specimens collected from pregnant women (n = 1,519) during February 2017-September 2018 and their infants (n = 1,080) during June 2017-March 2019 were tested for prenatal ZIKV infection by nucleic acid amplification tests or IgM antibody testing. Zika virus infection in pregnancy was present in 3.2% of pregnant women (incidence rate [IR] per 1,000 person-months = 5.9, 95% CI: 4.3-7.8). Presumptive ZIKV infection was present in 0.8% of infants (IR = 1.6, 95% CI: 0.7-2.9). Five percent of infants with prenatal ZIKV exposure or infection presented with Zika-associated abnormalities; 4.7% were small for gestational age. Understanding the risk of ZIKV infection during pregnancy and associated adverse outcomes can help inform counseling efforts.
Databáze: MEDLINE