Molecular mechanisms of neutron radiation dose effects on M 1 generation peas.

Autor: Xu D; School of Nuclear Science and Technology, Lanzhou University, Lanzhou 730000, China; Engineering Research Center for Neutron Application Technology, Ministry of Education, Lanzhou University, Lanzhou, 730000, China. Electronic address: xudp@lzu.edu.cn., Feng H; School of Life Sciences, Lanzhou University, Lanzhou, 730000, China., Li Y; School of Nuclear Science and Technology, Lanzhou University, Lanzhou 730000, China; Engineering Research Center for Neutron Application Technology, Ministry of Education, Lanzhou University, Lanzhou, 730000, China., Pan J; School of Life Sciences, Lanzhou University, Lanzhou, 730000, China., Yao Z; School of Nuclear Science and Technology, Lanzhou University, Lanzhou 730000, China; Engineering Research Center for Neutron Application Technology, Ministry of Education, Lanzhou University, Lanzhou, 730000, China.
Jazyk: angličtina
Zdroj: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine [Appl Radiat Isot] 2024 Oct; Vol. 212, pp. 111423. Date of Electronic Publication: 2024 Jul 03.
DOI: 10.1016/j.apradiso.2024.111423
Abstrakt: The dose effect of radiation has long been a topic of concern, but the molecular mechanism behind it is still unclear. In this study, dried pea seeds were irradiated with 252 Cf fission neutron source. Through analyzing the transcriptome and proteome of M 1 generation pea (Pisum sativum L.) leaves, we studied the molecular rule and mechanism of neutron dose effect. Our results showed three important rules of global gene expression in the studied dose range. The rule closely related to the neutron absorbed dose at the transcription and translation levels is: the greater the difference in neutron absorbed dose between two radiation treatment groups, the greater the difference in differential expression between the two groups and the control group. We also obtained important sensitive metabolic pathways of neutron radiation, as well as related key genes. Furthermore, the overall molecular regulation mechanism of dose effect was revealed based on the main functional items obtained. Our research results can be applied to appropriate radiation dose estimation and agricultural production practice.
Competing Interests: Declaration of competing interest No conflicts of interest exist.
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Databáze: MEDLINE
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