Association between hematological indices and blood glucose level among patients with type 2 diabetes.

Autor: Al-Dewachi AB; College of Medicine, University of Mosul-Mosul-Iraq, Mosul, Iraq. anmaraldewachi@yahoo.com., Al-Dewachi SO; Department of Pathology, College of Medicine, Ninevah University, Mosul, Iraq.
Jazyk: angličtina
Zdroj: Irish journal of medical science [Ir J Med Sci] 2024 Oct; Vol. 193 (5), pp. 2307-2312. Date of Electronic Publication: 2024 Jul 09.
DOI: 10.1007/s11845-024-03754-x
Abstrakt: Background: Diabetes mellitus is a major health problem with a variety of implications: cellular, metabolic, and hematological. Hematological alterations observed in type 2 diabetes are related to hyperglycemia and have a vital role in vascular-associated diabetes complications which could be used as a marker for these complications. The aim of this study is to assess the association between hematological indices and blood glucose levels in patients with type 2 diabetes attending outpatient clinics in Mosul.
Patients and Methods: A case-control study was done on 100 patients with type 2 diabetes and 100 healthy controls attending Alwafa Center for Diabetes and Endocrinology and four family medicine health centers in Mosul for the period 1st of January 2024-30th of March 2024. Data collection was done by a direct interview with participants. Hematological indices were tested by using an automatic hematology analyzer.
Results: Statistically significant differences in Hb were found between diabetic patients and controls (P = 0.007). The total WBC count, neutrophils, and lymphocytes were significantly higher in diabetic patients compared to controls (P = 0.001 for all). Moreover, platelet indices (platelets count and PDW) showed a significant difference between diabetic patients and controls (P = 0.004 and 0.000) respectively. In addition, total WBC count, neutrophil count, and lymphocytes show a statistically significant positive correlation with FBS (P = 0.026, 0.050, and 0.019) respectively.
Conclusion: This study revealed statistically significant differences in various hematological parameters between patients with type 2 diabetes and healthy controls. Regular testing of hematological indices helps in early detection and proper management of diabetic complications.
(© 2024. The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.)
Databáze: MEDLINE
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