Early Morbidities of Hypoxia-Ischemic Encephalopathy in Term Neonates With a Resistive Index as a Prognostic Indicator.

Autor:	G S G; Department of Pediatrics, Al-Ameen Medical College and Research Center, Vijayapura, IND., Yeli RK; Department of Radiology, Bijapur Lingayat District Educational (BLDE) (Deemed to Be University), Shri B M Patil Medical College Hospital and Research Centre, Vijayapura, IND., Nimbal V; Department of Radiodiagnosis, Bijapur Lingayat District Educational (BLDE) (Deemed to Be University), Shri B M Patil Medical College Hospital and Research Centre, Vijayapura, IND., S B D; Department of Radiology, Jagadguru Sri Shivarathreeshwara (JSS) Medical College, Mysore, IND., Kumar M P; Department of Radiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Mysore, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jun 08; Vol. 16 (6), pp. e61936. Date of Electronic Publication: 2024 Jun 08 (Print Publication: 2024).
DOI:	10.7759/cureus.61936
Abstrakt:	Background Acidosis, hypoxemia, and hypercarbia are symptoms of a syndrome known as perinatal asphyxia that occurs during the first and second stages of labor and shortly after delivery due to poor gas exchange. The Doppler technique is a non-invasive way to assess the risk of neurodevelopment damage in hypoxic-ischemic encephalopathy (HIE) that may be done at the patient's bedside without disturbing them. The study aims to evaluate cranial ultrasound findings in HIE and investigate the role of resistive index (RI) values assessed by color Doppler transcranial ultrasonography in predicting early morbidities in neonates with HIE within 72 hours of life. Methodology Prospective observational research was carried out at the north Karnataka region's tertiary newborn critical care unit. The study included 54 infants with HIE in total. The male-to-female ratio was 1.7:1, with 34 (63%) male and 20 (37%) female newborns. Results About 32 instances had grade I HIE, 8 had grade II HIE, and 14 had grade III HIE. In 35 instances (64.81%), the RI was normal; in 19 cases (35.19%), it was abnormal. Increased periventricular density and cerebral parenchyma echo density were common Doppler ultrasonography findings. Roughly 93% of people survived, and 7% of people died from HIE. Seizures (12.96%) and acute renal damage (33.33%) were the most frequent consequences. Conclusion In instances of HIE, the RI was revealed to be a favorable predictive indicator for newborn prognosis. Counseling and educating parents about early morbidities, anticipated long-term consequences, and the need for follow-up will all benefit from it. Additionally, color Doppler is a practical and secure diagnostic method for determining a newborn's level of HIE. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. The Institutional Ethical Committee of Shri B M Patil Medical College Hospital and Research Centre, Vijayapur issued approval BLDE (DU)/IEC/597/2022-23. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, G S et al.)
Databáze:	MEDLINE
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