Large airway wall vascularity in patients with asthma-COPD overlap: a bronchoscopy study.

Autor:	Dey S; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia., Lu W; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia.; Launceston Respiratory and Sleep Centre, Launceston, Australia., Weber HC; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia.; Department of Respiratory Medicine, Tasmanian Health Services, North-West Hospital, Burnie, Australia., Chia C; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia.; Launceston Respiratory and Sleep Centre, Launceston, Australia.; Department of Respiratory Medicine, Launceston General Hospital, Launceston, Australia., Pathinayake PS; Immune Health Program, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia., Wark PAB; Immune Health Program, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia.; Department of Respiratory Medicine, Monash University, Melbourne, Australia., Eapen MS; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia., Sohal SS; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia.; Launceston Respiratory and Sleep Centre, Launceston, Australia.
Jazyk:	angličtina
Zdroj:	ERJ open research [ERJ Open Res] 2024 Jul 08; Vol. 10 (4). Date of Electronic Publication: 2024 Jul 08 (Print Publication: 2024).
DOI:	10.1183/23120541.00002-2024
Abstrakt:	Large airway wall lamina propria in patients with asthma-COPD overlap is hypovascular with an increase in reticular basement membrane neoangiogenesis, reflecting smoking-related COPD-like pathology and potential epithelial-to-mesenchymal transition https://bit.ly/49DeoFX. Competing Interests: Conflict of interest: S.S. Sohal reports an honorarium for lectures from Chiesi, travel support from Chiesi, AstraZeneca and GSK, and research grants from Boehringer Ingelheim and Lung Therapeutics, outside the submitted work; and has served on the Small Airway Advisory Board for Chiesi Australia for which an honorarium has been received, all disclosures made outside the submitted work. Conflict of interest: The remaining authors have nothing to disclose. (Copyright ©The authors 2024.)
Databáze:	MEDLINE
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