Perichondritis of the auricle: bacterial or fungal? (A case series).

Autor: Hu M; Department of Otorhinolaryngology Head and Neck Surgery, Tianjin First Central Hospital, Tianjin, 300192, China.; Institute of Otolaryngology of Tianjin, Tianjin, China.; Key Laboratory of Auditory Speech and Balance Medicine, Tianjin, China.; Key Medical Discipline of Tianjin (Otolaryngology), Tianjin, China.; Quality Control Centre of Otolaryngology, Tianjin, China., Cheng Y; Department of Otorhinolaryngology Head and Neck Surgery, Tianjin First Central Hospital, Tianjin, 300192, China. cyan6398@sina.com.; Institute of Otolaryngology of Tianjin, Tianjin, China. cyan6398@sina.com.; Key Laboratory of Auditory Speech and Balance Medicine, Tianjin, China. cyan6398@sina.com.; Key Medical Discipline of Tianjin (Otolaryngology), Tianjin, China. cyan6398@sina.com.; Quality Control Centre of Otolaryngology, Tianjin, China. cyan6398@sina.com.
Jazyk: angličtina
Zdroj: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2024 Oct; Vol. 281 (10), pp. 5559-5562. Date of Electronic Publication: 2024 Jul 08.
DOI: 10.1007/s00405-024-08792-w
Abstrakt: Background: Suppurative perichondritis of the auricle is a common disease that can easily cause malformations if it develops into an uncontrolled infection. In nearly half of the cases, otolaryngologists cannot identify the pathogens involved.
Case Presentation: In the present work, we described two cases of pyogenic perichondritis, with negative on conventional culture. However, using metagenomic next-generation sequencing (mNGS), we detected fungal infections in the patients and after the patients were given anti-fungal treatment, the patients achieved a good prognosis.
Conclusions: These cases highlighted the possibility that fungi might be the involved pathogens in patients who have had multiple negative bacterial cultures, and mNGS should be applied in these cases. mNGS could be used as a supplement to traditional culture methods.
(© 2024. The Author(s).)
Databáze: MEDLINE
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