Use of Citicoline in Attention-Deficit/Hyperactivity Disorder: A Pilot Study.
| Autor: | Hübner IB; Programa de Pós-Graduação em Ciências Médicas, Universidade do Vale do Taquari (UNIVATES), Lajeado, Brazil., Scheibe DB; Programa de Pós-Graduação em Ciências Médicas, Universidade do Vale do Taquari (UNIVATES), Lajeado, Brazil., Marchezan J; Child Neurology Unit, Pediatrics Service, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil., Bücker J; Programa de Pós-Graduação em Ciências Médicas, Universidade do Vale do Taquari (UNIVATES), Lajeado, Brazil. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Clinical neuropharmacology [Clin Neuropharmacol] 2024 Sep-Oct 01; Vol. 47 (5), pp. 146-149. Date of Electronic Publication: 2024 Jun 24. |
| DOI: | 10.1097/WNF.0000000000000602 |
| Abstrakt: | Objectives: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurobehavioral disorder in school-aged children. Although there are several drug treatment options, some patients do not have adequate therapeutic responses to conventional medications or experience considerable adverse effects. Citicoline is an endogenous molecule that has beneficial effects on attention, impulsivity, and memory and is a potential treatment for ADHD. This study aimed to evaluate the effect of citicoline in pediatric patients diagnosed with ADHD. Methods: This randomized, crossover, double-blind, placebo-controlled clinical trial included with patients aged 7-12 years diagnosed with ADHD. Results: As a result, no statistically significant difference was noted between the use of citicoline and placebo in the evaluated parameters. The treatment had no adverse effects. Conclusions: Citicoline seems to be a safe molecule to be administered in the pediatric age group. Further studies are required to assess the therapeutic potential of citicoline in ADHD. Competing Interests: Conflicts of Interest and Source of Funding: The authors have no conflicts of interest to declare. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|