Clinical Reasoning and Challenges Faced With Onset Psychotic Symptoms in a Case of Combined Huntington's Disease and Gayet-Wernicke Encephalopathy.

Autor: Omri M; Department of Psychiatry and Psychotherapy, Klinikum Mutterhaus der Borromäerinnen, Trier, DEU., Ferhi M; Department of Psychiatry, Mohamed Taher Maamouri University Hospital, Nabeul, TUN., Oliveira Galvao M; Department of Psychiatry and Psychotherapy, Klinikum Mutterhaus der Borromäerinnen, Trier, DEU., Hamm O; Department of Psychiatry and Psychotherapy, Klinikum Mutterhaus der Borromäerinnen, Trier, DEU.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Jun 07; Vol. 16 (6), pp. e61875. Date of Electronic Publication: 2024 Jun 07 (Print Publication: 2024).
DOI: 10.7759/cureus.61875
Abstrakt: Physicians are occasionally confronted with patients presenting psychotic symptoms of organic origin. Therefore, precision in diagnosing the organic basis is pivotal for targeted treatment, addressing the underlying etiology. This case study delineates the nuanced phases of clinical reasoning employed to ascertain a diagnosis of Huntington's disease (HD), notably amidst concurrent alcohol dependence. A comprehensive clinical examination and meticulous review of the patient's medical history served as linchpins in guiding subsequent investigations toward identifying the etiological underpinnings of the psychotic symptomatology. Furthermore, this case sheds light on the uncommon overlap of HD and Wernicke's encephalopathy, compounding diagnostic complexities, especially given the polymorphic nature of HD. The diagnostic intricacies needed precise analysis of the clinical picture and a deep understanding of potential interactions between neurological pathologies and the deleterious effects of alcoholism on the nervous system.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Omri et al.)
Databáze: MEDLINE