Symptom Distress Before and After Heart Transplantation - A Longitudinal 5-Year Follow-Up.

Autor: Dalvindt M; Institute of Health Sciences at Lund University, Lund, Sweden.; Education Unit, Ystad County Hospital, Ystad, Sweden., Veungen HL; Department of Cardiothoracic Surgery, Lund University, Skåne University Hospital, Lund, Sweden., Kisch A; Institute of Health Sciences at Lund University, Lund, Sweden.; Department of Haematology at Skåne University Hospital, Lund, Sweden., Nozohoor S; Department of Cardiothoracic Surgery, Lund University, Skåne University Hospital, Lund, Sweden., Lennerling A; The Transplant Centre, Sahlgrenska University Hospital, Gothenburg, Sweden.; Institute of Health and Care Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Forsberg A; Institute of Health Sciences at Lund University, Lund, Sweden.; Department of Cardiothoracic Surgery, Lund University, Skåne University Hospital, Lund, Sweden.
Jazyk: angličtina
Zdroj: Clinical transplantation [Clin Transplant] 2024 Jul; Vol. 38 (7), pp. e15385.
DOI: 10.1111/ctr.15385
Abstrakt: Introduction: Symptom distress after heart transplantation (HTx) is a significant problem causing uncertainty, low self-efficacy, and psychological distress. Few studies have addressed self-reported symptoms. The aim was to explore self-reported symptom distress from time on the waiting list to 5 years after HTx and its association with self-reported psychological well-being, chronic pain, and fatigue in order to identify possible predictors of psychological or transplant specific well-being.
Methods: This multicenter, longitudinal cohort study includes 48 heart recipients (HTRs), 12 women, and 36 men, with a median age of 57 years followed from pretransplant to 5 years post-transplant. Symptom distress was explored by means of four instruments measuring psychological general wellbeing, transplant specific wellbeing, pain, and fatigue.
Results: Transplant specific well-being for the whole improved in a stepwise manner during the first 5 years compared to pretransplant. Heart transplant recipients with poor psychological wellbeing were significantly more burdened by symptom distress, in particular sleep problems and fatigue, for up to 5 years after HTx, and their transplant-specific well-being never improved compared to baseline. The prevalence of pain varied from 40% to 60% and explained a significant proportion of the variance in transplant-specific well-being, while psychological general well-being was mainly predicted by overall symptom distress.
Conclusion: The presence of distressing symptoms explains a significant proportion of poor psychological wellbeing both among HTRs reporting chronic pain and those without pain.
(© 2024 The Author(s). Clinical Transplantation published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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