Subacute Cerebral Infarct: An Unusual Cause of Radiotracer Uptake at 18 F-PSMA PET/CT.

Autor: Jain V; From the Divisions of Neuroradiology., McIntosh L; Oncologic and Molecular Imaging, Department of Radiology, UMass Chan Medical School, Worcester, MA.
Jazyk: angličtina
Zdroj: Clinical nuclear medicine [Clin Nucl Med] 2024 Sep 01; Vol. 49 (9), pp. 882-883. Date of Electronic Publication: 2024 Jul 05.
DOI: 10.1097/RLU.0000000000005373
Abstrakt: Abstract: Prostate-specific membrane antigen (PSMA) PET/CT has become an unparalleled modality in the diagnosis of primary and recurrent prostatic adenocarcinoma, often revealing sites of disease that were previously invisible on conventional imaging. In this 78-year-old man with suspected prostate cancer recurrence, PSMA PET/CT revealed focal radiotracer uptake in the brain, which would ordinarily raise suspicion for metastases, but was a false positive in the setting of a recent stroke. Increased PSMA uptake has been reported in subacute infarcts and primary and secondary brain tumors. Careful history and comparison with prior imaging are vital to avoid false-positive diagnosis in such patients.
Competing Interests: Conflicts of interest and sources of funding: none declared. L.M.: Bioclinica/Clario, Imaging Endpoints, WorldCare Clinical: consulting relationship for clinical trial reads, but no relevant conflicts for this manuscript.
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Databáze: MEDLINE