Telangiectatic osteosarcoma of the mandible-A rare case report and an insight into differential diagnosis.

Autor:	Kumar P; Department of Oral & Maxillofacial Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, India., Narayan B; Department of Oral & Maxillofacial Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, New Delhi, India. Electronic address: bhaskarnarayan9191@gmail.com., Urs AB; Department of Oral & Maxillofacial Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, New Delhi, India., Mohanty S; Department of Oral and Maxillofacial Surgery, Maulana Azad Institute of Dental Sciences, New Delhi, India., Augustine J; Department of Oral & Maxillofacial Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, New Delhi, India., Singh P; Department of Oral and Maxillofacial Surgery, Maulana Azad Institute of Dental Sciences, New Delhi, India., Khurana N; Director Professor and Head, Department of Pathology, Maulana Azad Medical College, New Delhi, India.
Jazyk:	angličtina
Zdroj:	Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia [Rev Esp Patol] 2024 Jul-Sep; Vol. 57 (3), pp. 225-229. Date of Electronic Publication: 2024 Jun 14.
DOI:	10.1016/j.patol.2024.05.001
Abstrakt:	Telangiectatic osteosarcoma (TOS) is a rare variant of osteosarcoma that typically affects young individuals and long bones. The case under discussion was seen in the mandible of a 57-year-old female and had rapidly grown in size within a week. Microscopically, the tumour was characterised by large vascular cavities surrounded by anaplastic cells. Thin lacy tumour osteoid was observed at various foci. Abundant multinucleated osteoclastic giant cells along with areas of necrosis were also noted. The tumour cells were positive for SATB2, while negative for Cytokeratin AE1/3, CD 34. Ki-67 positivity was observed in more than 50% of tumour cells. A diagnosis of high grade telangiectatic osteosarcoma was thus made. (Copyright © 2024 Sociedad Española de Anatomía Patológica. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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