Clinical impact of smoking on atrial fibrillation recurrence after pulmonary vein isolation.

Autor: Giomi A; Cardiology and Electrophysiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Santa Maria Nuova Hospital, Florence, Italy., Bernardini A; Cardiology and Electrophysiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Santa Maria Nuova Hospital, Florence, Italy; Department of Experimental and Clinical Medicine, University of Florence, Italy. Electronic address: andrea.bernardini@uslcentro.toscana.it., Perini AP; Cardiology and Electrophysiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Santa Maria Nuova Hospital, Florence, Italy., Ciliberti D; Department of Experimental and Clinical Medicine, University of Florence, Italy., Zaccaria CS; Cardiology and Electrophysiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Santa Maria Nuova Hospital, Florence, Italy; Department of Experimental and Clinical Medicine, University of Florence, Italy., Signorini U; Cardiology and Electrophysiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Santa Maria Nuova Hospital, Florence, Italy., Padeletti M; Cardiology and Electrophysiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Santa Maria Nuova Hospital, Florence, Italy., Milli M; Cardiology and Electrophysiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Santa Maria Nuova Hospital, Florence, Italy.
Jazyk: angličtina
Zdroj: International journal of cardiology [Int J Cardiol] 2024 Oct 15; Vol. 413, pp. 132342. Date of Electronic Publication: 2024 Jul 04.
DOI: 10.1016/j.ijcard.2024.132342
Abstrakt: Background: The clinical impact of smoking on atrial fibrillation (AF) recurrences after pulmonary vein isolation (PVI) have contradictory results in previous studies, performed on Asian populations.
Methods and Aim: Smoking habit and other cardiovascular risk-factors were assessed in patients who underwent their first radiofrequency PVI for symptomatic AF. The study aims to assess the clinical impact of smoking on AF recurrences after PVI in a contemporary European cohort of patients.
Results: The study included 186 consecutive patients (135 males [72.6%]) with a mean age of 63.4 ± 9.7 years. Current smokers resulted 29 (15.7%). No statistically significant baseline differences were detected between current smokers and non-current smokers. After a follow-up of 418 ± 246 days, AF recurrence was higher in currently smoking patients vs. non-currently smoker patients, the latter intended as a combination between previous smokers and never smokers (34.5% vs. 14% p = 0.01). A previous smoking habit was not associated with increased risk of AF recurrence when compared with patients who never smoked (13.2% vs. 14.6%, p = 0.23), while a current smoking habit impacted on AF recurrence in comparison with previous smokers (p = 0.01) and never smokers (p = 0.04). The increased incidence of AF recurrence in current smokers was consistent also considering only paroxysmal AF (31.4% vs 9.6%, p = 0.012) or persistent AF (50% vs 31.2%, p = 0.03). Smoking (HR =2.96 95% CI 1.32-6.64) and persistent AF (HR =2.64 95% CI 1.22-5.7) resulted independent predictors of AF recurrence.
Conclusion: Cigarette smoking is associated with an increased risk of AF recurrences after PVI, both in paroxysmal and in persistent AF.
Competing Interests: Declaration of competing interest Andrea Giomi: no disclosure. Andrea Bernardini: no disclosure. Alessandro Paoletti Perini: no disclosure. Cristiano Salvatore Zaccaria: no disclosure. Davide Ciliberti: no disclosure. Margherita Padeletti: no disclosure. Umberto Signorini: no disclosure. Massimo Milli: no disclosure.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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