Fatal Hymenolepis nana-associated visceral larva migrans in captive juvenile white-tailed antsangies (Brachytarsomysalbicauda).

Autor: Archer KR; International Zoo Veterinary Group, Station House, Parkwood Street, Keighley BD21 4NQ, UK., Waeschenbach A; Science, Natural History Museum, Cromwell Road, London SW7 5BD, UK., Griffin C; Science, Natural History Museum, Cromwell Road, London SW7 5BD, UK., Payne IL; Holly House Veterinary Hospital, 468 Street Lane, Moortown, Leeds LS17 6HA, UK., Houston J; PO Box 110 University, Port Moresby Nature Park, Goro-Kaeaga Road, Port Moresby National Capital District, Papua New Guinea., Littlewood DTJ; Science, Natural History Museum, Cromwell Road, London SW7 5BD, UK., Rich AF; International Zoo Veterinary Group, Station House, Parkwood Street, Keighley BD21 4NQ, UK. Electronic address: andrewrich@outlook.com.
Jazyk: angličtina
Zdroj: Journal of comparative pathology [J Comp Pathol] 2024 Jul; Vol. 212, pp. 32-41. Date of Electronic Publication: 2024 Jul 05.
DOI: 10.1016/j.jcpa.2024.05.005
Abstrakt: White-tailed antsangies (Brachytarsomys albicauda) are Madagascan rodents uncommonly kept in captivity. Hymenolepis nana is a cestode with an unusual life cycle, incorporating direct, indirect and autoinfective stages. This case series represents the first reported outbreak of H. nana cestodiasis in white-tailed antsangies, summarizing macroscopic and histological findings in four cases. On post-mortem examination (PME), numerous cysticerci were detected consistently throughout the intestinal serosa, liver, mesenteric lymphatic vasculature and mesenteric lymph nodes. Pancreatic cysticerci were observed in one case. Adult tapeworms, larvae and eggs were found only in the small intestine, and faecal egg shedding was a feature. Histopathological examination identified adult, larval and encysted cestodes within the respective gross lesions, with pulmonary, pancreatic and splenic involvement detected in a single case. The cestodes sampled on PME were identified by polymerase chain reaction and DNA sequencing, with H. nana confirmed in all cases. Visceral larva migrans was consistent throughout all specimens, in contrast with the natural infections of standard rodent hosts, and may be considered a likely pathological feature of H. nana infection in white-tailed antsangies.
Competing Interests: Declaration of competing interests The authors declared no conflicts of interest in relation to the research, authorship or publication of this article.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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