Long-term exposure to road traffic noise and acute lower respiratory infections in the Danish Nurse Cohort.

Autor: Zhang J; Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark. Electronic address: jzh@sund.ku.dk., Lim YH; Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Napolitano GM; Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Backalarz C; DELTA Acoustics, Hørsholm, Denmark., Mortensen LH; Denmark Statistic, Copenhagen, Denmark; Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Cole-Hunter T; Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Tuffier S; Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Bergmann M; Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., So R; Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark; Department of Epidemiology and Public Health, University College London, London, United Kingdom., Brandt J; Department of Environmental Science, Aarhus University, Roskilde, Denmark; iClimate, interdisciplinary Centre for Climate Change, Aarhus University, Roskilde, Denmark., Ketzel M; Department of Environmental Science, Aarhus University, Roskilde, Denmark; Global Centre for Clean Air Research (GCARE), University of Surrey, Guildford, United Kingdom., Loft S; Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Andersen ZJ; Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Jazyk: angličtina
Zdroj: Environment international [Environ Int] 2024 Aug; Vol. 190, pp. 108842. Date of Electronic Publication: 2024 Jul 04.
DOI: 10.1016/j.envint.2024.108842
Abstrakt: Background: Long-term exposure to road traffic noise is associated with cardiovascular disease, but the evidence on respiratory diseases is just emerging. We aimed to examine the association between long-term exposure to road traffic noise and the incidence of acute lower respiratory infections (ALRIs) in adults.
Methods: We followed 23,141 female nurses (age ≥ 44 years) from the Danish Nurse Cohort from baseline (1993 or 1999) to their first hospital contact (inpatient, outpatient, or emergency room) for ALRI, death, emigration or the end of 2015. The residential annual mean levels of road traffic noise (L den ) during the follow-up were estimated using the Nord2000 model. We applied time-varying Cox models to estimate the association of 3-year mean exposure to L den with ALRIs incidence and piecewise analysis to estimate the threshold of L den . We examined the robustness of the results by adjusting for residential exposure to air pollution, and the effect modification by attained age, socioeconomic status (SES), comorbidity, and lifestyle.
Results: During 18.5 years of follow-up, 2,004 nurses developed ALRIs. In a linear model, we detected a statistically significant positive association between L den and ALRI, with a hazard ratio (HR) of 1.11 (95 % confidence interval (CI): 1.04, 1.17) per 9.2 dB (interquartile range, IQR). We observed non-linear association with a threshold at 57 dB, above which the HR was 1.25 (95 % CI: 1.09, 1.43) per IQR. Further adjustment for PM 2.5 reduced the HRs slightly to 1.21 (95 % CI: 1.04, 1.40). The associations were stronger for nurses with asthma, and in those with lowest SES.
Conclusion: We present novel findings in support of the association between long-term exposure to road traffic noise and ALRIs, independent of air pollution, suggesting noise as a risk factor for infectious respiratory diseases.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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