Mapping the World Health Organization Disability Assessment Scale 2.0 to the EQ-5D-5L in patients with mental disorders.

Autor:	Abdin E; Research Division, Institute of Mental Health, Singapore, Singapore., Seet V; Research Division, Institute of Mental Health, Singapore, Singapore., Jeyagurunathan A; Research Division, Institute of Mental Health, Singapore, Singapore., Tan SC; Research Division, Institute of Mental Health, Singapore, Singapore., Mohmad Khalid MIS; Research Division, Institute of Mental Health, Singapore, Singapore., Mok YM; Department of Mood and Anxiety, Institute of Mental Health, Singapore, Singapore., Verma S; Department of Psychosis, Institute of Mental Health, Singapore, Singapore., Subramaniam M; Research Division, Institute of Mental Health, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Jazyk:	angličtina
Zdroj:	Expert review of pharmacoeconomics & outcomes research [Expert Rev Pharmacoecon Outcomes Res] 2024 Oct; Vol. 24 (8), pp. 1009-1015. Date of Electronic Publication: 2024 Jul 11.
DOI:	10.1080/14737167.2024.2376100
Abstrakt:	Objective: The current study aims to develop an algorithm for mapping the WHODAS 2.0 to the EQ-5D-5 L for patients with mental disorders. Methods: This cross-sectional study was conducted at the Institute of Mental Health and Community Wellness Clinics in Singapore between June 2019 and November 2022. We included four regression methods including the Ordinary Least Square (OLS) regression, the Tobit regression model (Tobit), the robust regression with MM estimator (MM), and the adjusted limited dependent variable mixture model (ALDVMM) to map EQ-5D-5 L utility scores from the WHODAS 2.0. Results: A total of 797 participants were included. The mean EQ-5D-5 L utility and WHODAS 2.0 total scores were 0.615 (SD = 0.342) and 11.957 (SD = 8.969), respectively. We found that the EQ-5D-5 L utility score was best predicted by the robust regression model with the MM estimator. Our findings suggest that the WHODAS 2.0 total scores were significantly and inversely associated with the EQ-5D-5 L utility scores. Conclusion: This study provides a mapping algorithm for converting the WHODAS 2.0 scores into EQ-5D-5 L utility scores which can be implemented using a simple online calculator in the following web application: https://eastats.shinyapps.io/whodas_eq5d/.
Databáze:	MEDLINE
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