Is there a need for screening of cervical HPV infections and carcinoma?

Autor: Miyagi E; Department of Obstetrics and Gynecology, Yokohama City University School of Medicine, Japan. Electronic address: emiyagi@yokohama-cu.ac.jp., Mizushima T; Department of Obstetrics and Gynecology, Yokohama City University School of Medicine, Japan.
Jazyk: angličtina
Zdroj: Best practice & research. Clinical obstetrics & gynaecology [Best Pract Res Clin Obstet Gynaecol] 2024 Sep; Vol. 96, pp. 102522. Date of Electronic Publication: 2024 Jun 15.
DOI: 10.1016/j.bpobgyn.2024.102522
Abstrakt: Antenatal cervical screening aims to detect cervical intraepithelial neoplasms as precancerous lesions and invasive cervical cancer. Whether this screening is performed routinely during pregnancy varies depending on each country's screening participation rates, guidelines, and the risks to the pregnant woman. In some countries with the high rate of routinely implemented cervical screening among the target women, women are recommended to defer cervical screening intentionally to post-delivery, though having screening in consultation with physicians may be possible if routine screening overlaps. However, when cervical screening rate in fertile women is low and the incidence of cervical cancer is high, cervical screening during pregnancy may play an important role in the early detection of cervical cancer. Cervical screening using high-risk human papillomavirus (HPV) testing is accepted worldwide as a highly sensitive and objective test method, and it should replace traditional primary cervical cytology in the future. However, the benefits and disadvantages of using HPV testing in pregnant women is unclear because a false positive rate may be increased due to pregnant women being generally under an immunosuppressed condition.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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