Outcomes of Biodegradable Temporizing Matrix for Soft Tissue Reconstruction of the Hand and Extremities.

Autor:	Struble SL; From the Division of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, Pa., Patel NK; Division of Plastic and Reconstructive Surgery, Department of Surgery, West Virginia University, Morgantown, W.Va., Graham EM; Section of Plastic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Mich., Tipps JA; From the Division of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, Pa.; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa., Vaile JR; From the Division of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, Pa., Leeflang EJ; Division of Plastic Surgery, Department of Surgery, University of Utah, Salt Lake City, Utah., Goodwin I; Division of Plastic Surgery, Department of Surgery, University of Utah, Salt Lake City, Utah., Mendenhall SD; From the Division of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, Pa.; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa.; Division of Orthopaedic Surgery, Children's Hospital of Philadelphia, Philadelphia, Pa.; From the Division of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, Pa.
Jazyk:	angličtina
Zdroj:	Plastic and reconstructive surgery. Global open [Plast Reconstr Surg Glob Open] 2024 Jul 03; Vol. 12 (7), pp. e5956. Date of Electronic Publication: 2024 Jul 03 (Print Publication: 2024).
DOI:	10.1097/GOX.0000000000005956
Abstrakt:	Background: NovoSorb biodegradable temporizing matrix (BTM) is a novel, bilayer, synthetic skin substitute made of biodegradable polyurethane foam covered with a sealing membrane. BTM has demonstrated excellent outcomes in burn literature; however, few studies have been published for hand and extremity soft tissue reconstruction. Methods: All patients who underwent extremity reconstruction with BTM from 2018 to 2023 were reviewed. Demographics, presentations, and clinical outcomes were recorded. Results: A total of 86 cases from 54 patients (53.7% pediatric; age range: 0-81 years) were included. Common indications included trauma (36%), infection (18.6%), and malignancy (11.6%). BTM was placed over exposed tendon (38.4%), bone (19%), joints (12.8%), nerves (8.1%), and/or blood vessels (7%). BTM served as temporary wound coverage in 26 cases. Complications included hematoma (8.1%), infection (4.7%), and spontaneous delamination (4.7%). Wound closure was successfully obtained without flap use in 93.3%. Poor BTM take was associated with peripheral vascular disease, hypertension, immunosuppression, and BTM hematoma and infection (<0.05). Conclusion: This study contributes to the growing body of evidence favoring BTM use in challenging reconstructive cases. Although prospective comparative studies are forthcoming, BTM likely has broad applications in reconstructive surgery. Competing Interests: Author Shaun D. Mendenhall is an educational consultant for PolyNovo, the manufacturer of NovoSorb BTM. All the other authors have no financial interest to declare in relation to the content of this article. (Copyright © 2024 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons.)
Databáze:	MEDLINE
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