Envenomation by the Indian ornamental tarantula (Poecilotheria regalis): A case report on treatment with Latrodectus mactans antivenom.

Autor: José Alejandro GA; Departamento de Investigación Química y Farmacológica de Productos Naturales, Facultad de Química, Universidad Autónoma de Querétaro, Centro Universitario S/N, 76010, Querétaro, Querétaro, Mexico. Electronic address: alejandro.gr@uaq.mx., Juan M; Laboratorio de Inmunología y Vacunas, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Querétaro, 76230, Querétaro, Mexico; Aracnario, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Querétaro, Av. De Las Ciencias S/N, 76230, Juriquilla, Mexico., Luis CB; Aracnario, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Querétaro, Av. De Las Ciencias S/N, 76230, Juriquilla, Mexico., Fátima Pamela SM; Hospital General Regional No. 2 El Marqués, Instituto Mexicano Del Seguro Social, Circuito Universidades KM 1 S/N, 76269, El Marqués, Querétaro, Mexico., Ivonne B; Posgrado en Ciencias Químico Biológicas, Facultad de Química, Universidad Autónoma de Querétaro, Centro Universitario S/N, 76010, Querétaro, Querétaro, Mexico., Diana Laura PT; Posgrado en Ciencias Químico Biológicas, Facultad de Química, Universidad Autónoma de Querétaro, Centro Universitario S/N, 76010, Querétaro, Querétaro, Mexico., Ashly M; Posgrado en Ciencias Químico Biológicas, Facultad de Química, Universidad Autónoma de Querétaro, Centro Universitario S/N, 76010, Querétaro, Querétaro, Mexico.
Jazyk: angličtina
Zdroj: Toxicon : official journal of the International Society on Toxinology [Toxicon] 2024 Aug 28; Vol. 247, pp. 107842. Date of Electronic Publication: 2024 Jul 01.
DOI: 10.1016/j.toxicon.2024.107842
Abstrakt: Poecilotheria spiders are considered theraphosids of underestimated clinical importance, with bites from these species inducing symptoms such as severe pain and intense muscle cramps. However, there is no specific treatment for the envenomation caused by these species, which, while native to India and Sri Lanka, are widely distributed worldwide. The present study reports the case of a 31-year-old man bitten by a Poecilotheria regalis specimen. The patient's clinical presentation was similar to Latrodectus envenomation, and patient was treated with an L. mactans antivenom. Most of patient's symptoms improved (fasciculations, pain, erythema, and local swelling), except muscle cramps. A toxicological study conducted on mice did not show that L. mactans antivenom has a neutralizing effect on the toxicity of P. regalis. The present report discusses the envenoming process of Poecilotheria species and the possible neutralizing effect exerted by L. mactans antivenom.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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