The Global Prevalence of Seborrheic Dermatitis: A Systematic Review and Meta-Analysis.

Autor:	Polaskey MT; Chicago Medical School, Rosalind Franklin University of Medicine and Science, Chicago, Illinois.; Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Chang CH; College of Medicine, University of Illinois, Chicago., Daftary K; Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Fakhraie S; Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Miller CH; Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Chovatiya R; Chicago Medical School, Rosalind Franklin University of Medicine and Science, Chicago, Illinois.; Center for Medical Dermatology and Immunology Research, Chicago, Illinois.
Jazyk:	angličtina
Zdroj:	JAMA dermatology [JAMA Dermatol] 2024 Aug 01; Vol. 160 (8), pp. 846-855.
DOI:	10.1001/jamadermatol.2024.1987
Abstrakt:	Importance: Seborrheic dermatitis is a prevalent chronic inflammatory skin disease, yet its global prevalence, pathogenesis, and epidemiology remain inadequately defined. Objective: To provide a detailed estimation of the global prevalence of seborrheic dermatitis, analyze demographic variations, and explore differences in various settings. Data Sources: Embase, PubMed, Scopus, and Cochrane Database of Systematic Reviews were searched from inception through October 2023. Study Selection: Original investigations on seborrheic dermatitis prevalence were included after duplicate screening of titles, abstracts, and full articles, including only studies with clinician-diagnosed cases. Data Extraction and Synthesis: Following PRISMA guidelines, data were extracted and quality was assessed independently by multiple reviewers. A random-effects model using restricted maximum likelihood was used for meta-analysis and subgroup analyses. Main Outcome and Measure: The primary outcome was the pooled estimate of global seborrheic dermatitis prevalence. Results: From 1574 identified articles, 121 studies were included, encompassing 1 260 163 individuals and revealing a pooled global seborrheic dermatitis prevalence of 4.38% (95% CI, 3.58%-5.17%), with significant heterogeneity (I2 = 99.94%). Subgroup analyses showed variations by age, with a higher prevalence in adults (5.64% [95% CI, 4.01%-7.27%]) compared to children (3.70% [95% CI, 2.69%-4.80%]) and neonates (0.23% [95% CI, 0.04%-0.43%]). Geographic analyses indicated variability, with the highest prevalence in South Africa (8.82% [95% CI, 3.00%-14.64%]) and the lowest in India (2.62% [95% CI, 1.33%-3.92%]). Conclusions and Relevance: This comprehensive meta-analysis provides a detailed estimation of the global prevalence of seborrheic dermatitis, highlighting significant variability across different demographics and settings.
Databáze:	MEDLINE
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