Occurrence of hepatitis B and C virus infection in socioeconomic population strata from Recife, Pernambuco, Northeast Brazil.

Autor: Mariz CA; Fundação Oswaldo Cruz, Instituto Aggeu Magalhães - Recife (PE), Brazil.; Faculdade de Medicina de Olinda - Olinda (PE), Brazil., Braga C; Fundação Oswaldo Cruz, Instituto Aggeu Magalhães - Recife (PE), Brazil., Albuquerque MFPM; Fundação Oswaldo Cruz, Instituto Aggeu Magalhães - Recife (PE), Brazil., Luna CF; Fundação Oswaldo Cruz, Instituto Aggeu Magalhães - Recife (PE), Brazil., Salustiano DM; Laboratório Central de Saúde Pública Dr. Milton Bezerra Sobral - Recife (PE), Brazil., Freire NM; Laboratório Central de Saúde Pública Dr. Milton Bezerra Sobral - Recife (PE), Brazil., Morais CNL; Fundação Oswaldo Cruz, Instituto Aggeu Magalhães - Recife (PE), Brazil., Lopes EP; Universidade Federal de Pernambuco, Faculty of Medicine of Recife - Recife (PE), Brazil.
Jazyk: English; Portuguese
Zdroj: Revista brasileira de epidemiologia = Brazilian journal of epidemiology [Rev Bras Epidemiol] 2024 Jul 01; Vol. 27, pp. e240033. Date of Electronic Publication: 2024 Jul 01 (Print Publication: 2024).
DOI: 10.1590/1980-549720240033
Abstrakt: Objective: To estimate the probability of infection with hepatitis B (HBV) and C (HCV) viruses in different socioeconomic strata of the population of Recife, Northeast Brazil.
Methods: Study carried out from samples obtained in a survey of residents of a large urban center that had a population base and stratified sampling with random selection of households using the "Brazil Sample" package in the R software. HBV (HBsAg) and anti-HCV was performed using immunochromatographic tests. In cases positive for HBsAg, anti-HBc and HBeAg were tested using chemiluminescence, as well as HBV-DNA using real-time PCR. For cases positive for anti-HCV, the search for this antibody was repeated by chemiluminescence and for HCV-RNA by real-time PCR. The occurrence of HBsAg and anti-HCV cases in the general population was estimated based on a theoretical negative binomial distribution.
Results: Among 2,070 samples examined, 5 (0.24%) were HBsAg and 2 (0.1%) anti-HCV positive. The majority of cases had self-reported skin color as black/brown (6/7), education level up to high school (6/7), a steady partner (5/7) and lived in an area of low socioeconomic status (5/7).
Conclusion: The occurrence of HBsAg and anti-HCV was lower than those previously found in population-based studies and slightly lower than the most recent estimates. Individuals with lower socioeconomic status should be a priority target of public health policies.
Databáze: MEDLINE