Invasive Breast Cancer of No Special Type With Osteoclast-Like Giant Cells: A Cytological Clue Providing the Final Diagnosis for Histology.
| Autor: | Veekmans T; Department of Pathology, KU Leuven-University of Leuven, University Hospitals Leuven, Leuven, BEL., Weynand B; Department of Pathology, KU Leuven-University of Leuven, University Hospitals Leuven, Leuven, BEL., Floris G; Department of Pathology, KU Leuven-University of Leuven, University Hospitals Leuven, Leuven, BEL. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Apr 18; Vol. 16 (4), pp. e58518. Date of Electronic Publication: 2024 Apr 18 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.58518 |
| Abstrakt: | Breast cancer associated with osteoclast-like giant cells (OGCs) refers to a morphological pattern of invasive breast carcinoma of non-special type. Their presence is sometimes subtle, but OGCs can be appreciated both histologically and immunohistochemically. The origin of OGCs as well as their implication for prognosis remain debated. We describe the case of a 65-year-old woman, wherein the presence of OGCs in the fine-needle aspiration cytology of a metastatic axillary lymph node suggested the final diagnosis on histology. The differential diagnosis is broad, and here we provide evidence for strict cytological-histological correlation when dealing with unusual breast lesions. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Veekmans et al.) |
| Databáze: | MEDLINE |
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