A Case of Pancreatic Ductal Adenocarcinoma in an Elderly Adult With Heterotaxy Syndrome.
| Autor: | Lin Z; Internal Medicine, NewYork-Presbyterian (NYP) Brooklyn Methodist Hospital, Brooklyn, USA., Rahman A; Internal Medicine, NewYork-Presbyterian (NYP) Brooklyn Methodist Hospital, Brooklyn, USA., Quintero S; Gastroenterology, NewYork-Presbyterian (NYP) Brooklyn Methodist Hospital, Brooklyn, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Jul 02; Vol. 16 (7), pp. e63664. Date of Electronic Publication: 2024 Jul 02 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.63664 |
| Abstrakt: | Heterotaxy is a syndrome characterized by a spectrum of anatomical anomalies in organ lateralization due to embryological errors. It frequently involves intrathoracic organs, especially the heart, leading to congenital abnormalities. Abdominal organs can also be affected, causing clinical features such as sepsis from asplenia or intestinal volvulus; however, these are less studied. Currently, there is no data on the relationship between heterotaxy and malignancy. We present an interesting case of an elderly adult admitted for a workup of newly diagnosed pancreatic ductal carcinoma, who was found to have heterotaxy of the stomach and spleen, with eventual tumor invasion of these organs. This case suggests that heterotaxy may increase the risk of gastrointestinal malignancy and result in a poorer prognosis due to the complexity of tumor resection involving additional organs. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Lin et al.) |
| Databáze: | MEDLINE |
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