Visual acuity and optic nerve size assessed by magnetic resonance imaging in optic nerve hypoplasia.

Autor: Butterfield S; California Pacific Medical Center, Department of Ophthalmology, San Francisco, California. Electronic address: butters@sutterhealth.org., Benson JC; Mayo Clinic Department of Radiology, Rochester, Minnesota., Eckel L; Mayo Clinic Department of Radiology, Rochester, Minnesota., Mansukhani S; Mayo Clinic Department of Ophthalmology, Rochester, Minnesota., White L; Mayo Clinic Department of Biomedical Statistics and Informatics, Jacksonville, Florida., Hodge D; Mayo Clinic Department of Biomedical Statistics and Informatics, Jacksonville, Florida., Mohney BG; Mayo Clinic Department of Ophthalmology, Rochester, Minnesota.
Jazyk: angličtina
Zdroj: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus [J AAPOS] 2024 Aug; Vol. 28 (4), pp. 103964. Date of Electronic Publication: 2024 Jun 30.
DOI: 10.1016/j.jaapos.2024.103964
Abstrakt: We investigated the relationship between optic nerve (ON) size and visual acuity in children with optic nerve hypoplasia (ONH). The medical records of patients <19 years with ONH who underwent brain magnetic resonance imaging (MRI) and visual acuity assessment were reviewed. ON diameter at orbital and cisternal segments was assessed independently by two neuroradiologists and compared with visual acuity. ON diameter <1.7 mm represented a cutoff, below which was significantly associated with visual acuity of 20/200 or worse (P = 0.04) and above which was significantly associated with visual acuity of 20/40 or better (P = 0.004). ON diameter measured with MRI may provide an early prognostic indication of visual potential for children with ONH.
(Copyright © 2024 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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