Effectiveness of non-pharmacological therapies for chronic pain in people with autoimmune diseases in Africa: A protocol for a systematic review and meta-analysis.

Autor: Gebremeskel GG; Department of Adult Health Nursing, School of Nursing, College of Health Science, Aksum University, Aksum, Tigray, Ethiopia., Haile TG; Department of Maternity and Neonatal Nursing, School of Nursing, College of Health Science, Aksum University, Aksum, Tigray, Ethiopia., Gebrewahd GT; Department of Critical Care Nursing, School of Nursing, College of Health Science, Aksum University, Aksum, Tigray, Ethiopia., Hailay A; Department of Adult Health Nursing, School of Nursing, College of Health Science, Aksum University, Aksum, Tigray, Ethiopia., Aberhe W; Department of Adult Health Nursing, School of Nursing, College of Health Science, Aksum University, Aksum, Tigray, Ethiopia., Mebrahtom G; Department of Adult Health Nursing, School of Nursing, College of Health Science, Aksum University, Aksum, Tigray, Ethiopia., Zereabruk K; Department of Adult Health Nursing, School of Nursing, College of Health Science, Aksum University, Aksum, Tigray, Ethiopia., Negash AI; Department of Adult Health Nursing, School of Nursing, College of Health Science, Aksum University, Aksum, Tigray, Ethiopia., Gebrekidan H; Department of Child Health Nursing, School of Nursing, College of Health Science, Aksum University, Aksum, Tigray, Ethiopia., Tadesse DB; Department of Adult Health Nursing, School of Nursing, College of Health Science, Aksum University, Aksum, Tigray, Ethiopia.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2024 Jul 02; Vol. 19 (7), pp. e0306564. Date of Electronic Publication: 2024 Jul 02 (Print Publication: 2024).
DOI: 10.1371/journal.pone.0306564
Abstrakt: Background: Autoimmune diseases affect 5-10% of the global population and cause chronic pain and impaired functionality. Chronic pain management involves pharmacological and non-pharmacological interventions, with non-pharmacological options gaining attention as safe, effective, and cost-effective alternatives. However, further research is needed to determine the effectiveness of these therapies in African patients with autoimmune diseases, as existing evidence varies.
Methods: This review protocol has been registered in the International Prospective Register of Systematic Reviews (PROSPERO, CRD42023449896). Electronic databases (PubMed, Africa Index Medicus, Cochrane Library, CINAHL, PsycINFO, and Web of Science) will be used for searching published articles. The study will use R for data synthesis, employing a random-effects meta-analysis approach to calculate pooled effect sizes, assess heterogeneity using the I2 statistic, and evaluate publication bias. In conclusion, this protocol aims to fill the knowledge gap on non-pharmacological therapies for chronic pain in patients with autoimmune diseases in Africa. It will potentially enhance evidence-based decision-making to improve pain management and, hence, the quality of life of people with autoimmune diseases in Africa.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Gebremeskel et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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